先天性外中耳畸形(3)——形态学研究进展

张天宇;傅窈窈;

1:复旦大学附属眼耳鼻喉科医院眼耳鼻整形外科

摘要
<正>先天性外中耳畸形是继唇腭裂之后最为常见的颅面部出生缺陷,发病率约为1/10 000,其主要表现为单侧或双侧耳郭畸形、外耳道狭窄或闭锁及中耳畸形。男女患者比例约为2.5∶1,单侧发病多于双侧发病,比例约为4∶1;可单独发生,亦可伴发心脏、脊柱等其它器官畸形([1,2])。先天性外中耳畸形的发病原因尚不明确,药物、毒物或感染等因素引起的胚胎期发育停滞、基因表达异常、血管损害等均可能致病;少于15%的患者
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作者
张天宇;傅窈窈;
参考文献

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张天宇傅窈窈