弥散张量成像应用于听神经瘤患者术前面神经定位可行性的初步研究

A Pilot Study on the Feasibility of Diffusion Tensor Imaging for Preoperative Location of Facial Nerve in Patients with Acoustic Neuroma

蔡林彬;杨军;

1:上海交通大学医学院附属新华医院耳鼻咽喉-头颈外科上海市耳鼻疾病转化医学重点实验室(No.14DZ2260300)上海交通大学医学院耳科学研究所

摘要
目的探讨听神经瘤患者术前应用弥散张量成像(diffusion tensor imaging,DTI)定位面神经的可行性。方法对6例听神经瘤患者术前进行DTI扫描定位面神经,将结果与术中所见面神经位置(分为肿瘤的上级、下级、前方和后方)比较,验证DTI的准确性。结果 6例患者中5例术前DTI面神经的重建结果与术中所见一致,DTI的准确率为83.3%(5/6),且DTI及术中面神经定位均显示面神经在肿瘤前方;1例患者术前DTI显示面神经在肿瘤前方,而术中见肿瘤压迫致面神经移位变形至肿瘤上极。结论 DTI对听神经瘤患者术前面神经定位有较高的准确率及良好的应用前景,有助于确定最佳手术路径、缩短寻找面神经的时间,降低面神经损伤概率。
关键词
弥散张量成像;术前定位;听神经瘤;面神经
基金项目(Foundation):
作者
蔡林彬;杨军;
参考文献

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