小鼠耳蜗性聋的关键通路和差异表达基因分析
Identification of Key Pathways and Genes in Mice of Cochlear Deafness using Bioinformatics Analysis
杨媛媛;黄冠江;陶源;
1:北京大学深圳医院耳鼻咽喉科
2:浙江大学医学院附属第二医院耳鼻咽喉科
1 Ding B,Walton JP,Zhu X,et al.Age-related changes in Na,K-ATPase expression,subunit isoform selection and assembly in the stria vascularis lateral wall of mouse cochlea[J].Hear Res,2018,367:59.
2 Hosokawa K,Hosokawa S,Ishiyama G,et al.Immunohistochemical localization of Nrf2 in the human cochlea[J].Brain Res,2018,1700:1.
3 Peyvandi AA,Roozbahany NA,Peyvandi H,et al.Critical role of SDF-1/CXCR4 signaling pathway in stem cell homing in the deafened rat cochlea after acoustic trauma[J].Neural Regen Res,2018,13:154.
4 吴振恭,褚汉启.耳蜗KCNQ1基因表达及其与耳聋的关系[J].听力学及言语疾病杂志,2006,14:144.
5 Bettini S,Franceschini V,Astolfi L,et al.Human mesenchymal stromal cell therapy for damaged cochlea repair in nod-scid mice deafened with kanamycin[J].Cytotherapy,2018,20:189.
6 Atkinson PJ,Dong Y,Gu S,et al.Sox2 haploinsufficiency primes regeneration and Wnt responsiveness in the mouse cochlea[J].J Clin Invest,2018,128:1641.
7 李琦,施雯玉,常青,等.外源性脑源性神经因子对遗传性聋动物模型耳蜗形态和功能的影响[J].临床耳鼻咽喉头颈外科杂志,2017,31:1347.
8 Yoshimura H,Takumi Y,Nishio SY,et al.Deafness gene expression patterns in the mouse cochlea found by microarray analysis[J].PLoS One,2014,9:e92547.
9 Pashaiasl M,Ebrahimi M,Ebrahimie E.Identification of the key regulating genes of diminished ovarian reserve (DOR) by network and gene ontology analysis[J].Mol Biol Rep,2016,43:923.
10 Muller H,Schmidt D,Dreher F,et al.Gene ontology analysis of the centrosome proteomes of drosophila and human[J].Commun Integr Biol,2011,4:308.
11 Kim I,Choi S,Kim S.BRCA-pathway:a structural integration and visualization system of TCGA breast cancer data on KEGG pathways[J].BMC Bioinformatics,2018,19(Suppl 1):42.
12 Lee S,Park Y,Kim S.MIDAS:mining differentially activated subpaths of KEGG pathways from multi-class RNA-seq data[J].Methods,2017,124:13.
13 Dennis GJ,Sherman BT,Hosack DA,et al.DAVID:database for annotation,visualization,and integrated discovery[J].Genome Biol,2003,4:P3.
14 Weidner C,Steinfath M,Wistorf E,et al.A protocol for using gene set enrichment analysis to identify the appropriate animal model for translational research[J].J Vis Exp,2017,126:e55768.
15 Li L,Wang X,Xiao G,et al.Integrative gene set enrichment analysis utilizing isoform-specific expression[J].Genet Epidemiol,2017,41:498.
16 Qiao Y,Zhang L,Xu K,et al.Inflammatory lesions of cochlea in murine cytomegalovirus-infected mice with hearing loss[J].Cell Biochem Biophys,2012,62:281.
17 Zou J,Pyykko I,Sutinen P,et al.Vibration induced hearing loss in guinea pig cochlea:expression of TNF-alpha and VEGF[J].Hear Res,2005,202:13.
18 Riva C,Donadieu E,Magnan J,et al.Age-related hearing loss in CD/1 mice is associated to ROS formation and HIF target proteins up-regulation in the cochlea[J].Exp Gerontol,2007,42:327.
19 Tadros SF,D'Souza M,Zhu X,et al.Apoptosis-related genes change their expression with age and hearing loss in the mouse cochlea[J].Apoptosis,2008,13:1303.
20 Kovacovicova K,Awadova T,Mikel P,et al.In vitro maturation of mouse oocytes increases the level of Kif11/Eg5 on meiosis II spindles[J].Biol Reprod,2016,95:18.
21 Johnson K,Moriarty C,Tania N,et al.Kif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube[J].Dev Biol,2014,387:73.
22 Kapanidou M,Curtis NL,Bolanos-Garcia VM.Cdc20:at the crossroads between chromosome segregation and mitotic exit[J].Trends Biochem Sci,2017,42:193.
23 Buniello A,Ingham NJ,Lewis MA,et al.Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing[J].EMBO Mol Med,2016,8:191.
24 Menardo J,Tang Y,Ladrech S,et al.Oxidative stress,inflammation,and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea[J].Antioxid Redox Signal,2012,16:263.
25 Someya S,Yamasoba T,Prolla TA,et al.Genes encoding mitochondrial respiratory chain components are profoundly down-regulated with aging in the cochlea of DBA/2J mice[J].Brain Res,2007,1182:26.