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500 Hz不同时程短纯音骨导眼性前庭肌源性诱发电位研究

Comparison of 500 Hz Tone Burst Evoked Bone-conducted Ocular Evoked Myogenic Potential with Different Filter Settings

樊小勤;林颖;刘嘉伟;董晨;王敏姣;钟波;查定军;

1:空军军医大学西京医院耳鼻咽喉头颈外科

2:中国计量科学研究院

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摘要

目的比较500 Hz不同时程短纯音诱发骨导眼性前庭肌源性诱发电位(bone conducted ocular vestibular evoked myogenic potential, BC-oVEMP)的波形差异,以探讨BC-oVEMP最佳时程的刺激声参数。方法选择20例听力正常的健康青年人(男女各10例,年龄20～25岁,平均22.0±2.0岁)为研究对象,由听觉诱发电位仪输出500 Hz不同时程短纯音,经功率放大器放大,由激振器在受试者头颅正中近发际线(Fz)处施加骨导振动,单侧记录BC-oVEMP的n1潜伏期、P1潜伏期、n1-P1波间期、n1-P1振幅、振幅比、双侧不对称比。结果 500 Hz不同时程(以上升时间-平台期-下降时间表示,单位为ms)刺激声均引出BC-oVEMP,相同上升/下降时间、不同平台期的短纯音(2-0-2、2-1-2、2-2-2、2-4-2、2-8-2 ms)诱发的BC-oVEMP的n1潜伏期、P1潜伏期、n1-P1波间期、n1-P1振幅、振幅比、双侧不对称比差异无统计学意义(P>0.05);n1-P1振幅随平台期的延长先增大再减小,其中2-1-2、2-2-2 ms的短纯音诱发BC-oVEMP的n1-P1振幅最大。相同平台期、不同上升/下降时间(1-2-1、2-2-2 ms)的短纯音诱发BC-oVEMP的n1潜伏期、P1潜伏期差异有统计学意义(P<0.05),随上升/下降时间的延长,n1、P1潜伏期均出现延长;n1-P1波间期、n1-P1振幅、振幅比、双侧不对称比差异无统计学意义(P>0.05);n1-P1振幅随上升/下降时间的延长而降低。结论 BC-oVEMP在听力健康青年人中可诱发出良好的波形,500 Hz上升/下降时间为1 ms、平台期为2 ms的短纯音可作为BC-oVEMP优先刺激声。

关键词

骨导振动;椭圆囊;前庭功能;前庭肌源性诱发电位

基金项目(Foundation):

国家自然科学基金面上项目(81670924,81470695)

作者

樊小勤;林颖;刘嘉伟;董晨;王敏姣;钟波;查定军;

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骨导振动椭圆囊前庭功能前庭肌源性诱发电位

本文作者相关文章

樊小勤林颖刘嘉伟董晨王敏姣钟波查定军