隐性听力损失——临床听力学的新挑战(1)·病因与损伤机制

冀飞;

1:解放军总医院耳鼻咽喉头颈外科解放军总医院耳鼻咽喉研究所

2:解放军总医院耳鼻咽喉头颈外科聋病防治北京市重点实验室

3:解放军总医院耳鼻咽喉头颈外科聋病教育部重点实验室

摘要
<正>近年来,区别于以往的一种获得性感音神经性听力损失——"隐性听力损失(hidden hearing loss,HHL)"逐渐被人们认识,一方面,临床出现主诉噪声下言语识别困难但纯音听力正常的患者,且在噪声接触人群和老龄人群中多见;另一方面,深入的动物模型研究也发现噪声暴露和衰老除引起可恢复的暂时性毛细胞损伤之外,还导致了耳蜗内毛细胞与蜗神经I型传入纤维之间的部分突触的永久性损伤,而这种突触损伤并未影响听觉电生理阈值;临床
关键词
基金项目(Foundation):
军事医学创新工程和青年培育项目(16QNP133);; 国家自然科学基金面上项目(81670940;81670941;81570933);; 首都卫生发展科研专项重点攻关项目(2016-1-5014);; 北京科技创新基地培育与发展专项(z151100001615050)
作者
冀飞;
参考文献

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冀飞