鼓室注射糖皮质激素治疗高压氧不耐受的难治性突发性聋
Clinical Observation of Intratympanic Methylprednisolone Perfusion in Refractory Sudden Hearing Loss Patients with Hyperbaric Oxygen (HBO) Intolerance
李曼;袁东升;刘建兵;董晓斌;颜小梅;蔡跃峰;柏正群;佘万东;
1:江苏省盐城市大丰人民医院耳鼻喉科
2:南京大学医学院附属鼓楼医院耳鼻咽喉头颈外科
摘要关键词基金项目(Foundation):作者参考文献1 Crane RA,Camilon M,Nguyen S,et al.Steroids for treatment of sudden sensorineural hearing loss:a meta-analysis of randomized controlled trials[J].Laryngoscope,2015,125:209.
2 中华医学会耳鼻咽喉头颈外科学分会.中华耳鼻咽喉头颈外科杂志编辑委员会.突发性聋的诊断和治疗指南(2015)[J].中华耳鼻咽喉头颈外科杂志,2015,50:443.
3 Stachler RJ,Chandrasekher SS,Archer SM,et al.Chinical practice guideline:sudden hearing loss[J].Otolaryngol Head Neck Surg,2012,146(Suppl):S1.
4 Lamm K,Lamm C,Arnold W.Effect of isobaric oxygen versus hyperbaric oxygen on the normal and noise-damaged hypoxic and ischemic guinea pig inner ear[J].Adv Otorhinolaryngol,1998,54:59.
5 王亚林,汪银凤.不同浓度甲泼尼龙琥珀酸钠鼓室给药后在豚鼠血浆和外淋巴中的代谢[J].中华耳鼻咽喉头颈外科杂志,2009,44:853.
6 张慧平,屈永涛,王荣国,等.高压氧联合鼓室灌注激素治疗突发性耳聋的疗效及对血液流变学的影响[J].中国老年学,2016,36:4863.
7 Yang CH,Wu RW,Hwang CF.Comparison of intratympanic steroid injection,hyperbaric oxygen and combination therapy in refractory sudden sensorineural hearing loss[J].Otol Neurotol,2013,34:1411.
8 徐鸿翔,张莉,周谅,等.麻黄素液滴鼻对提高高压氧治疗患者耐受性的观察[J].海军医学杂志,2008,29:21.
9 DaiY,Lu L,Hou J,et al.Intratympanic methylprednisolone perfusion as a salvage treatment for profound idiopathic sudden sensorineural hearing loss[J].J Laryngol Otol,2017,131:404.
10 戴艳红,佘万东.鼓室局部给药后内耳药代动力学研究进展[J].听力学及言语疾病杂志,2009,17:395.
11 Agrahari V,Agrahari V,Mitra AK.Inner ear targeted drug delivery:what does the future hold[J]?Ther Deliv,2017,8:179.