颞骨巨细胞修复性肉芽肿临床分析

The Clinical Analysis of Giant Cell Reparative Granuloma in the Temporal Bone

廖卡稀;冯勃;韩东一;杨仕明;戴朴;韩维举;申卫东;刘军;赵辉;彭涛;

1:川北医学院第二附属医院

2:南充市中心医院耳鼻咽喉头颈外科

3:中国人民解放军总医院耳鼻咽喉头颈外科

摘要
目的分析颞骨巨细胞修复性肉芽肿(giant cell reparative granuloma,GCRG)的临床特点。方法回顾经病理确诊为颞骨GCRG的6例患者的临床资料,结合相关文献分析颞骨GCRG的临床特点及诊治方法。结果 6例(男、女各3例)均为单侧病变,其中有5例主要表现有听力减退,3例有耳闷胀感伴耳鸣,2例有颞区肿物伴疼痛,1例面瘫(面神经功能HBⅡ级)。3例患侧外耳道见粉红色肿物或脓性分泌物,未窥及鼓膜,2例鼓膜浑浊,1例已行鼓膜置管;鼓室导抗图1例A型,1例As型,3例C型,1例未作该检查;CT示颞骨区、颅中窝等处有膨胀性占位性病变,骨质多呈溶骨性改变;MRI示病变部位表现为T1WI和T2WI混杂低信号。所有患者行颅底、颞骨、颞下窝肿物切除术,5例经颅中窝进路、1例经颞-蝶进路完成手术;1例术后辅助放射治疗。术后病理诊断均为颞骨GCRG,随访23年,6例均无复发转移。结论颞骨巨细胞修复性肉芽肿临床表现多样,确诊需依靠病理学检查;治疗方法首选手术切除;当无法完全切除肿物时,术后应考虑放射治疗,预后较好。
关键词
颞骨;巨细胞修复性肉芽肿;诊断;治疗
基金项目(Foundation):
作者
廖卡稀;冯勃;韩东一;杨仕明;戴朴;韩维举;申卫东;刘军;赵辉;彭涛;
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