氧化应激损伤与HEI-OC1细胞株中Prestin表达的相关性分析
Prestin Expression in HEI-OC1 Cells With Oxidative Stress Damage
王军义;赖晓敏;龚丽娟;夏源;王致;
1:广东药科大学公共卫生学院
2:广州市第十二人民医院
摘要关键词基金项目(Foundation):作者参考文献1 Henderson D,Bielefeld EC,Harris KC,et al.The role of oxidative stress in noise-induced hearing loss[J].Ear Hear,2006,27:1.
2 Riva C,Donadieu E,Magnan J,et al.Age-related hearing loss in CD/1mice is associated to ROS formation and HIF target proteins up-regulation in the cochlea[J].Exp Gerontol,2007,42:327.
3 Van De Water TR,Lallemend F,Eshraghi AA,et al.Caspases,the enemy within,and their role in oxidative stress-induced apoptosis of inner ear sensory cells[J].Otol Neurotol,2004,25:627.
4 Sugahara K,Rubel EW,Cunningham LL.JNK signaling in neomycin-induced vestibular hair cell death[J].Hear Res,2006,221:128.
5 Sha SH,Chen FQ,Schacht J.Activation of cell death pathways in the inner ear of the aging CBA/J mouse[J].Hear Res,2009,254:92.
6 Zheng J,Shen W,He DZ,et al.Prestin is the motor protein of cochlear outer hair cells[J].Nature,2000,405:149.
7 Liberman MC,Gao J.Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier[J].Nature,2002,419:300.
8 Kalinec GM,Webster P,Lim DJ,et al.A cochlear cell line as an in vitro system for drug ototoxicity screening[J].Audiol Neurootol,2003,8:177.
9 Wang Z,Liu Y,Han N,et al.Profiles of oxidative stress-related microRNA and mRNA expression in auditory cells[J].Brain Res,2010,1346:14.
10 何献君,梁晓冬,吕晓峰,等.超氧化物歧化酶应用研究状态[J].中国医药指南,2010,8:37.
11 Gross J,Machulik A,Amarjargal N,et al.Expression of prestin mRNA in the organotypic culture of rat cochlea[J].Hear Res,2005,204:183.
12 Yang C,Zhang W,Liu XL,et al.Localization of prestin and expression in the early period after radiation in mice[J].Eur Arch Otorhinolaryngol,2014,271:3333.
13 Yang K,Huang ZW,Liu ZQ,et al.Long-term administration of salicylate enhances prestin expression in rat cochlea[J].International Journal of Audiology,2009,48:18.
14 陈秉,夏源,王海涛,等.噪声性听力损失与耳蜗外毛细胞Prestin蛋白的相关性分析[J].中国工业医学杂志,2015,28:92.
15 Xia A,Song Y,Wang R,et al.Prestin regulation and function in residual outer hair cells after noise-induced hearing loss[J].PLoS One,2013,8:e82602.
16 Parham K.Prestin as a biochemical marker for early detection of acquired sensorineural hearing loss[J].Med Hypotheses,2015,85:130.