低频重复经颅磁刺激治疗耳鸣的疗效分析

The Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation on Tinnitus

朱琼瑶;王慧;

1:上海交通大学附属第六人民医院耳鼻咽喉头颈外科

摘要

目的探讨低频重复经颅磁刺激治疗耳鸣的有效性和安全性。方法选取听力正常的主观性耳鸣患者102例,其中颅鸣患者34例(2665岁,平均53±12.59岁),耳鸣患者68例(3165岁,平均53±12.59岁),耳鸣患者68例(3169岁,平均51±12.29岁);采用1Hz低频脉冲刺激患者左侧颞顶部,每次一次性连续给予1 000次脉冲刺激,脉冲间隔时间为10s,5次/周,连续2周。所有患者治疗前后采用视觉模拟量表(visual-analogue scale,VAS)评估耳鸣的严重程度。结果治疗后,34例颅鸣患者中,24例颅鸣减轻或消失,总有效率为70.59%(24/34),其中2例患者自觉颅鸣完全消失(5.88%,2/34),22例自觉颅鸣响度减轻(64.71%,22/34),治疗前VAS平均分为5.09±1.01分,治疗后降为3.06±1.77分;68例耳鸣患者总有效率为64.71%(44/68),44例耳鸣减轻或消失(64.71%,44/68),其中1例耳鸣完全消失(1.47%,1/68),43例自觉耳鸣减轻(63.24%,43/68);治疗前VAS评分为5.68±1.51分,治疗后降为3.75±2.11分。两组患者治疗前后纯音听阈无显著变化,且无一例出现头痛、头晕、头皮灼伤、癫痫发作、耳鸣加重等不良反应。结论低频重复经颅磁刺激治疗耳鸣安全有效,其中颅鸣患者效果更佳。

关键词

经颅磁刺激;耳鸣;疗效

基金项目(Foundation):

作者

朱琼瑶;王慧;

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朱琼瑶王慧