连续鼓室注射糖皮质激素初始治疗突发性聋的效果分析
张宇;高中;刘亚军;杨皖菁;周波;李丹;肖键;王勇;
1:湖北医药学院附属东风医院耳鼻咽喉头颈外科





1 Stachler RJ,Chandrasekhar SS,Archer SM,et al.Clinical practice guideline:sudden hearing loss[J].OtolaryngologyHead and Neck Surgery,2012,146(3Suppl):S1.
2 Sharma K,Goswami SC,Baruah DK.Use of intratympanic steroid as a primary treatment for sudden sensorineural hearing loss[J].Journal of the Indian Medical Association,2010,108:148.
3 Labatut T,Daza MJ,Alonso A.Intratympanic steroids as primary initial treatment of idiopathic sudden sensorineural hearing loss.The Hospital Universitario Ramony Cajal experience and review of the literature[J].European Archives of Otorhino-laryngology,2013,270:2823.
4 中华耳鼻咽喉头颈外科杂志编辑委员会,中华医学会耳鼻咽喉头颈外科学分会.突发性聋的诊断和治疗指南(2005年,济南)[J].中华耳鼻咽喉头颈外科杂志,2006,41:569.
5 中国突发性聋多中心临床研究协作组.中国突发性聋分型治疗的多中心临床研究[J].中华耳鼻咽喉头颈外科杂志,2013,48:355.
6 Wilson WR,Byl FM,Laird N.The efficacy of steroids in the treatment of idiopathic sudden hearing loss.A double-blind clinical study[J].Archives of Otolaryngology,1980,106:772.
7 Masuda M,Kanzaki S,Minami S,et al.Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss[J].Otology&Neurotology,2012,33:1142.
8 Hamid M,Trune D.Issues,indications,and controversies regarding intratympanic steroid perfusion[J].Current Opinion in Otolaryngology&Head and Neck Surgery,2008,16:434.
9 Canlon B,Meltser I,Johansson P,et al.Glucocorticoid receptors modulate auditory sensitivity to acoustic trauma[J].Hearing Research,2007,226:61.
10 Trune DR,Canlon B.Corticosteroid therapy for hearing and balance disorders[J].Anatomical Record,2012,295:1928.
11 Silverstein H,Choo D,Rosenberg SI,et al.Intratympanic steroid treatment of inner ear disease and tinnitus(preliminary report)[J].Ear Nose&Throat Journal,1996,75:468.
12 Parnes LS,Sun AH,Freeman DJ.Corticosteroid pharmacokinetics in the inner ear fluids:an animal study followed by clinical application[J].The Laryngoscope,1999,109(7Pt2):1.
13 Arnold W,Senn P,Hennig M,et al.Novel slow-and fast-type drug release round-window microimplants for local drug application to the cochlea:an experimental study in guinea pigs[J].Audiology&Neuro-otology,2005,10:53.
14 Haynes DS,O'Malley M,Cohen S,et al.Intratympanic dexamethasone for sudden sensorineural hearing loss after failure of systemic therapy[J].The Laryngoscope,2007,117:3.
15 Ahn JH,Han MW,Kim JH,et al.Therapeutic effectiveness over time of intratympanic dexamethasone as salvage treatment of sudden deafness[J].Acta Oto-laryngologica,2008,128:128.
16 Wu HP,Chou YF,Yu SH,et al.Intratympanic steroid injections as a salvage treatment for sudden sensorineural hearing loss:a randomized,double-blind,placebo-controlled study[J].Otology&Neurotology,2011,32:774.
17 王春花,李立群,李玉环,等.甲基强的松龙鼓室注射与全身应用治疗突发性聋的疗效比较[J].听力学及言语疾病杂志,2014,22:201.
18 Labatut T,Daza MJ,Alonso A.Intratympanic steroids as primary initial treatment of idiopathic sudden sensorineural hearing loss[J].European Archives of Oto-Rhino-Laryngology,2012,270:2823.
19 李晖,刘莉,郭筠芳.鼓室注射地塞米松治疗突发性聋的疗效及影响因素分析[J].听力学及言语疾病杂志,2013,21:539.
20 Filipo R,Attanasio G,Russo FY,et al.Intratympanic steroid therapy in moderate sudden hearing loss:a randomized,triple-blind,placebo-controlled trial[J].The Laryngoscope,2013,123:774.
21 Dispenza F,Amodio E,De Stefano A,et al.Treatment of sudden sensorineural hearing loss with transtympanic injection of steroids as single therapy:a randomized clinical study[J].European Archives of Oto-rhino-laryngology,2011,268:1273.
22 Rauch SD,Halpin CF,Antonelli PJ,et al.Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss:a randomized trial[J].JAMA,2011,305:2071.
23 Robey AB,Morrow T,Moore GF.Systemic side effects of transtympanic steroids[J].The Laryngoscope,2010,120(Suppl 4):S217.
24 Yoshioka M,Naganawa S,Sone M,et al.Individual differences in the permeability of the round window:evaluating the movement of intratympanic gadolinium into the inner ear[J].Otology&Neurotology,2009,30:645.