耳蜗螺旋神经节细胞形态及计数的研究进展
肖茜;刘洋;闵美平;荣威林;张志远;
1:南昌大学第一附属医院耳鼻咽喉科
2:南昌大学第一附属医院神经外科





1 Rattay F,Potrusil T,Wenger C,et al.Impact of morphometry,myelinization and synaptic current strength on spike conduction in human and cat spiral ganglion neurons[J].PLoS One,2013,8:e79256.
2 Seyyedi M,Eddington DK,Nadol JB Jr,et al.Effect of monopolar and bipolar electric stimulation on survival and size of human spiral ganglion cells as studied by postmortem histopathology[J].Hear Res,2013,302:9.
3 Zheng XY,Henderson D,McFadden SL,et al.The role of the cochlear efferent system in acquired resistance to noiseinduced hearing loss[J].Hear Res,1997,104:191.
4 Géléoc GS,Holt JR.Sound strategies for heaing restoration[J].Science,2014,344:1241061.
5 Zheng XY,Ding DL,McFadden SL,et al.Evidence that inner hair cells are the major source of cochlear summating potentials[J].Hear Res,1997,113:76.
6 Chen I,Limb CJ,Ryugo DK.The effect of cochelar-implant-mediated electrical stimualtion on sopiral ganglion cells in congenitally deaf white cats[J].J Assoc Res Otolaryngol,2010,11:587.
7 Coate TM,Kelley MW.Making connections in the inner ear:recent insights into the development of spiral ganglion neurons and their connectivity with sensory hair cells[J].Semin Cell Dev Biol,2013,24:460.
8 Engle JR,Tinling S,Recanzone GH,et al.Age-related hearing loss in rhesus monkeys is correlated with cochlear histopathologies[J].PLoS One,2013,8:e55092.
9 Richter CP,Kumar G,Webster E,et al.Unbiased counting of neurons in the cochlea of developing gerbils[J].Hear Res,2011,278:43.
10 Kong WJ,Yin ZD,Fan GR,et al.Time sequence of auditory nerve and spiral ganglion cell degeneration following chronic kanamycin-induced deafness in the guinea pig[J].Brain Res,2010,1331:28.
11 Schmitz HM,Johnson SB,Santi PA.Kanamycin-furosemide ototoxicity in the mouse cochlea:a 3-dimensional analysis[J].Otolaryngol Head Neck Surg,2014,150:666.
12 Nayagam BA,Muniak MA,Ryugo DK.The spiral ganglion:connecting the peripheral and central auditory systems[J].Hear Res,2011,278:2.
13 Huang LC,Thorne PR,Housley GD,et al.Spatiotemporal definition of neurite outgrowth,refinement and retraction in the developing mouse cochlea[J].Deveropment,2007,134:2925.
14 Cho SI,Gao SS,Xia A,et al.Mechanisms of hearing loss after blast injury to the ear[J].PLoS One,2013,8:e67618.
15 Alam SA,Ikeda K,Oshima T,et al.Cisplatin-induced apoptotic cell death in mongolian gerbil cochlea[J].Hear Res,2000,141:28.
16 刘强和,罗香林,耿宛平,快速老化小鼠的听功能和耳蜗螺旋神经元的增龄性变化[J].山东大学耳鼻喉眼学报,2008,22:215.
17 聂深,向明亮,浓晨凌,等.卡那霉素联合吠塞米致聋小鼠耳蜗螺旋神经节细胞的退化变性及其EFR3A蛋白的表达[J].中华耳鼻咽喉头颈外科杂志,2014,49:930.
18 薛秋红,陈佳,龚树生.强噪声暴露下豚鼠耳蜗螺旋神经节细胞凋亡及Caspase一3的表达[J].听力学及言语疾病杂志,2007,15:208.
19 Olgun Y,Kirkim G,Kolatan E,et al.Otoprotective effect of recombinant erythropoietin in a model of newborn hypoxicischemic encephalopathy[J].Int J Pediatr Otorhinolaryngol,2013,77:739.
20 Choi MY,Yeo SW,Park KH.Hearing restoration in a deaf animal model with intravenous transplantation of mesenchymal stem cells derived from human umbilical cord blood[J].Biochemical and Biophysical Research Communications,2012,427:629.
21 Keithley EM,Feldman ML.The spiral ganglion and hair cells of Bronx waltzer mice[J].Hear Res,1983,12:381.
22 Spoendlin H,Brun JP.The block-surface technique for evaluation of cochlear pathology[J].Arch Otorhino-laryngol,1974,208:137.
23 Bohne BA,Harding GW.Combined organ of corti/modiolus technique f or preparing mammalian cochleas for quantitative microscopy[J].Hear Res,1993,71:114.
24 Johnson SB,Schmitz HM,Sant PA.TSLIM imaging and a morphometric analysis of the mouse spiral ganglion[J].Hearing Research,2011,278:34.
25 Howe HA.The reaction of the cochlear nerve to distrution of its endorgan:a study on deaf albino cats[J].J Comput Neurol,1934,62,73e79.
26 丁大连,王坚,郑向阳.耳蜗毛细胞和螺旋神经节以及神经纤维的联合定量观察[J].中国耳鼻咽喉颅底外科杂志,1998,4:200.
27 付勇,丁大连.大鼠耳蜗螺旋神经节细胞的定量观察[J].中西医结合耳鼻咽喉科杂志,2010,19:1.
28 方耀云,姚行齐,姜泗长,等,老化豚鼠耳蜗毛细胞和螺旋神经节细胞定量研究[J].中国体视学与图像分析,1996,1:64.
29 Schettino AE,Lauera AM.The efficiency of design-based stereology in estimating spiral ganglion populations in mice[J].Hear Res,2013,304:153.
30 方耀云,姜泗长,李玉,等.老年人螺旋神经节形态变化及定量的研究[J].中华老年医学杂志,1998,17:297.
31 Miller JM,Le Prell CG,Prieskorn DM,et al.Delayed neurotrophin treatment from fllowing deafness rescues spiral ganglion cells from death and promotes regrowth of auditory nerve peripheral processes:effects of brainderived neurotrophic factor and fibroblast growth factor[J].J Neurosci Res,2007,85:1959.
32 Fujita K,Hakuba N,Hata R,et al.Ginsenoside Rb1protects against damage to the spiralganglion cells after cochlear ischemia[J].Neurosci Lett,2007,415:113.
33 Nie C,Hu H,Shen C,et al.Expression of EFR3Ain the mouse cochlea during degeneration of spiral ganglion following hair cell loss[J].PLoS One,2015,10:e0117345.
34 Wrzeszcz A,Reuter G,Nolte I,et al.Spiral ganglion neuron quantification in the guinea pig cochlea using confocal laser scanning microscopy compared to embedding methods[J].Hear Res,2013,306:145.