鼓室内与静脉注射糖皮质激素治疗伴糖耐量异常突发性聋疗效比较

The Effectiveness of Intratympanic Steroid Therapy and Systemic Steroid Therapy on the treatment of Idiopathic Sudden Sensorineural Hearing Loss Patients with Damaged Glucose Tolerance

汤智平;吴湘萍;邱诺庆;陈庆利;梁志晟;梁银弟;田淑婷;

1:广东省东莞康华医院耳鼻喉科

摘要
目的比较糖皮质激素鼓室内注射与静脉给药对伴糖耐量异常的突发性聋患者的疗效。方法采用随机数字法,将50例伴糖耐量异常的初治单侧突发性聋患者随机平均分为鼓室注射组(地塞米松鼓室内注射)和静脉给药组(地塞米松静脉滴注),两组患者均同期接受相同的改善微循环及营养神经药物治疗。治疗期间每隔3天对患者进行纯音听阈测试,比较两组患者疗效。结果所有患者在治疗过程中平均听阈均逐渐下降,治疗后15天时静脉注射组患者平均听阈由治疗前的85.4±5.6dB HL下降至48.2±4.9dB HL,鼓室给药组由84.8±5.6dB HL下降至31.7±4.6dB HL,鼓室注射组患者总有效率为84.00%(21/95),较静脉给药组(68.00%,17/25)高(P<0.05)。结论采用糖皮质激素鼓室内注射对伴糖耐量异常的突发性聋患者的疗效较静脉给药的疗效更好。
关键词
鼓室内注射;突发性聋;糖耐量异常
基金项目(Foundation):
作者
汤智平;吴湘萍;邱诺庆;陈庆利;梁志晟;梁银弟;田淑婷;
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