听神经病谱系障碍患者时域间隔感知能力的研究

The Ability of Temporal Gap Detection in Listeners with Auditory Neuropathy Spectrum Disorder

王硕;董瑞娟;王媛;刘冬鑫;陈静;吴燕君;

1:首都医科大学附属北京同仁医院北京市耳鼻咽喉科研究所耳鼻咽喉头颈科学教育部重点实验室(首都医科大学)

摘要
目的探讨听神经病谱系障碍患者的时域间隔感知能力。方法使用美国加州大学尔湾分校开发的时域间隔感知能力测试软件,分别测试成年听力正常者(12例)、感音神经性听力损失者(12例)和听神经病谱系障碍者(15例)能够分辨出刺激声中无声间隔的最小时长,即时域间隔感知(temporal gap dection,TGD)阈值,比较三组受试者TGD的差异。结果三组受试者左右耳间TGD阈值差异均无统计学意义(P>0.05);听力正常组、感音神经性听力损失组和听神经病谱系障碍组双耳平均TGD阈值分别为3.97±1.12、3.62±1.14、13.72±9.89ms,感音神经性听力损失组TGD阈值与听力正常组差异无统计学意义(P>0.05),而听神经病谱系障碍组TGD阈值显著高于听力正常组和感音神经性听力损失组(P<0.01)。结论听神经病谱系障碍患者听觉系统的时域间隔感知能力下降,且个体差异较大。
关键词
时域间隔感知;感音神经性听力损失;听神经病谱系障碍
基金项目(Foundation):
国家自然科学基金(81200754);; 2012北京市科技新星计划(Z121107002512033);; 北京市自然科学基金面上项目(7122034);; 首都卫生发展科研专项基金(首发2011-1017-04);; 首都医科大学基础-临床科研合作基金(12JL46)联合资助
作者
王硕;董瑞娟;王媛;刘冬鑫;陈静;吴燕君;
参考文献

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