糖尿病对听觉系统的影响及其机制

郝瑾;龚树生;

1:首都医科大学附属北京同仁医院耳鼻咽喉头颈外科

2:首都医科大学附属北京友谊医院耳鼻咽喉头颈外科

摘要
<正>糖尿病既作为一个独立的疾病,又作为心脑血管疾病、癌症、微血管病变等疾病的危险因素,备受关注。中国糖尿病患病率正迅速增长,根据2010年美国糖尿病学会(American Diabetes Association,ADA)标准进行的2010年中国慢病监测暨糖尿病专题调查结果显示,中国成人糖尿病患病率为11.6%,糖尿病前期患病率为50.1%;由此推测,中
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郝瑾;龚树生;
参考文献

1 徐瑜,毕宇芳,王卫庆,等.中国成人糖尿病流行与控制现状--2010年中国慢病监测暨糖尿病专题调查报告解读[J].中华内分泌代谢杂志,2014,30:184.

2 陈兴宝,唐玲,陈慧云,等.2型糖尿病并发症对患者治疗费用的影响评估[J].中国糖尿病杂志,2003,11:238.

3 Gardner TW,Abcouwer SF,Barber AJ,et al.An integrated approach to diabetic retinopathy research[J].Arch Ophthalmol,2011,129:230.

4 Bainbridge KE,Hoffman HJ,Cowie CC.Diabetes and hearing impairment in the United States:audiometric evidence from the National Health and Nutrition Examination Survey,1999to 2004[J].Ann Intern Med,2008,149:1.

5 Bainbridge KE,Hoffman HJ,Cowie CC.Risk factors for hearing impairment among U.S.adults with diabetes:National Health and Nutrition Examination Survey 1999-2004[J].Diabetes Care,2011,34:1540.

6 Kakarlapudi V,Sawyer R,Staecker H.The effect of diabetes on sensorineural hearing loss[J].Otol Neurotol,2003,24:382.

7 Du Y,Heidemann C,G wald A,et al.Prevalence and comorbidity of diabetes mellitus among non-institutionalized older adults in Germany-results of the national telephone health interview survey'German Health Update(GEDA)'2009[J].BMC Public Health,2013,13:166.

8 Mitchell P,Gopinath B,McMahon CM,et al.Relationship of Type 2diabetes to the prevalence,incidence and progression of age-related hearing loss[J].Diabet Med,2009,26:483.

9 Panchu P.Auditory acuity in type 2diabetes mellitus[J].Int J Diabetes Dev Ctries,2008,28:114.

10 Lerman-Garber I,Cuevas-Ramos D,Valdés S,et al.Sensorineural hearing loss--a common finding in early-onset type 2diabetes mellitus[J].Endocr Pract,2012,18:549.

11 Sakuta H,Suzuki T,Yasuda H,et al.Type 2diabetes and hearing loss in personnel of the Self-Defense Forces[J].Diabetes Res Clin Pract,2007,75:229.

12 李鹃,张天宇,沈建中,等.听性脑干反应和畸变产物耳声发射在糖尿病患者听功能检测中的应用[J].临床耳鼻咽喉头颈外科杂志,2007,21:875.

13 Austin DF,Konrad-Martin D,Griest S,et al.Diabetesrelated changes in hearing[J].Laryngoscope,2009,119:1788.

14 Gupta S,Baweja P,Mittal S,et al.Brainstem auditory evoked potential abnormalities in type 2diabetes mellitus[J].N Am J Med Sci,2013,5:60.

15 Konrad-Martin D,Austin DF,Griest S,et al.Diabetesrelated changes in auditory brainstem responses[J].Laryngoscope,2010,120:150.

16 Huang CR,Lu CH,Chang HW,et al.Brainstem auditory evoked potentials study in patients with diabetes mellitus[J].Acta Neurol Taiwan,2010,19:33.

17 Sasso FC,Salvatore T,Tranchino G,et al.Cochlear dysfunction in type 2diabetes:a complication independent of neuropathy and acute hyperglycemia[J].Metabolism,1999,48:1346.

18 Frisina ST,Mapes F,Kim S,et al.Characterization of hearing loss in aged type II diabetics[J].Hear Res,2006,211:103.

19 Di Nardo W,Ghirlanda G,Paludetti G,et al.Distortionproduct otoacoustic emissions and selective sensorineural loss in IDDM[J].Diabetes Care,1998,21:1317.

20 Ottaviani F,Dozio N,Neglia CB,et al.Absence of otoacoustic emissions in insulin-dependent diabetic patients:is there evidence for diabetic cochleopathy[J]?J Diabetes Complications,2002,16:338.

21 Lisowska G,Namys owski G,Morawski K,et al.Cochlear dysfunction and diabetic microangiopathy[J].Scand Audiol Suppl,2001,52:199.

22 Jacobs PG,Konrad-Martin D,McMillan GP,et al.Influence of acute hyperglycemia on otoacoustic emissions and the medial olivocochlear reflex[J].J Acoust Soc Am,2012,131:1296.

23 Lee H,Sohn SI,Jung DK,et al.Sudden deafness and anterior inferior cerebellar artery infarction[J].Stroke,2002,33:2807.

24 van Duinkerken E,Schoonheim MM,Sanz-Arigita EJ,et al.Resting-state brain networks in type 1diabetic patients with and without microangiopathy and their relation to cognitive functions and disease variables[J].Diabetes,2012,61:1814.

25 Smith TL,Raynor E,Prazma J,et al.Insulin-dependent diabetic microangiopathy in the inner ear[J].Laryngoscope,1995,105(3Pt 1):236.

26 McQueen CT,Baxter A,Smith TL,et al.Non-insulindependent diabetic microangiopathy in the inner ear[J].J Laryngol Otol,1999,113:13.

27 Ishikawa T,Naito Y,Taniguchi K.Hearing impairment in WBN/Kob rats with spontaneous diabetes mellitus[J].Diabetologia,1995,38:649.

28 Lee HS,Kim KR,Chung WH,et al.Early sensorineural hearing loss in ob/ob mouse,an animal model of type 2diabetes[J].Clin Exp Otorhinolaryngol,20081:211.

29 Fujita T,Yamashita D,Katsunuma S,et al.Increased inner ear susceptibility to noise injury in mice with streptozotocininduced diabetes[J].Diabetes,2012,61:2980.

30 Kariya S,Cureoglu S,Fukushima H,et al.Comparing the cochlear spiral modiolar artery in type-1and type-2diabetes mellitus:a human temporal bone study[J].Acta Med Okayama,2010,64:375.

31 Antonetti DA,Klein R,Gardner TW.Diabetic retinopathy[J].N Engl J Med,2012,366:1227.

32 Qian H,Ripps H.Neurovascular interaction and the pathophysiology of diabetic retinopathy[J].Exp Diabetes Res,2011,2011:693426.

33 Tarr JM,Kaul K,Chopra M,et al.Pathophysiology of diabetic retinopathy[J].ISRN Ophthalmol,2013,2013:343560.

34 Zhang W,Liu H,Rojas M,et al.Anti-inflammatory therapy for diabetic retinopathy[J].Immunotherapy,2011,3:609.

35 Gologorsky D,Thanos A,Vavvas D.Therapeutic interventions against inflammatory and angiogenic mediators in proliferative diabetic retinopathy[J].Mediators Inflamm,2012,2012:629452.

36 Wang J,Xu X,Elliott MH,et al.Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascularleakage[J].Diabetes,2010,59:2297.

37 El-Remessy AB,Behzadian MA,Abou-Mohamed G,et al.Experimental diabetes causes breakdown of the bloodretina barrier by a mechanism involving tyrosinenitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor[J].Am J Pathol,2003,162:1995.

38 Wang J,Xu X,Elliott MH,et al.Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascularleakage[J].Diabetes,2010,59:2297.

39 Xu HZ,Song Z,Fu S,et al.RPE barrier breakdown in diabetic retinopathy:seeing is believing[J].J Ocul Biol Dis Infor,2011,4:83.

40 Wang X,Wang G,Wang Y.Intravitreous vascular endothelial growth factor and hypoxia-inducible factor 1ain patients with proliferativediabetic retinopathy[J].Am J Ophthalmol,2009,148:883.

41 Campos EC,Gattegna R,Raimondi MC,et al.Angiogenesis:possible analogies between the eye and the inner ear[J].Med Hypotheses,2012,78:644.

42 Picciotti PM,Torsello A,Cantore I,et al.Expression of vascular endothelial growth factor and its receptors in the cochlea of various experimental animals[J].Acta Otolaryngol,2005,125:1152.

43 Liu F,Xia M,Xu A.Expression of VEGF,iNOS,and eNOS is increased in cochlea of diabetic rat[J].Acta Otolaryngol,2008,128:1178.

44 Liew G,Klein R,Wong TY.The role of genetics in susceptibility to diabetic retinopathy[J].Int Ophthalmol Clin,2009,49:35.

45 Hu C,Zhang R,Yu W,et al.CPVL/CHN2genetic variant is associated with diabetic retinopathy in Chinese type 2diabetic patients[J].Diabetes,2011,60:3085.

46 Fu YP,Hallman DM,Gonzalez VH,et al.Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County,Texas[J].J Ophthalmol,2010,2010:861291.

47 Sheu WH,Kuo JZ,Lee IT,et al.Genome-wide association study in a Chinese population with diabetic retinopathy[J].Hum Mol Genet,2013,22:3165.

48 Chen P,Ong RT,Tay WT,et al.A Study Assessing the Association of Glycated Hemoglobin A1C(HbA1C)Associated Variants with HbA1C,Chronic Kidney Disease and Diabetic Retinopathy in Populations of Asian Ancestry[J].PLoS One,2013,8:e79767.

49 Kowluru RA,Santos JM,Mishra M.Epigenetic modifications and diabetic retinopathy[J].Biomed Res Int,2013,2013:635284.

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郝瑾龚树生