青少年喉乳头状瘤恶变为鳞状细胞癌一例分析

葛平江;梅平;程秋惠;盛晓丽;张思毅;陈少华;

1:广东省人民医院广东省医学科学院耳鼻咽喉-头颈外科

2:广东省人民医院广东省医学科学院病理科

摘要
目的探讨青少年喉癌的临床特点及治疗方法。方法回顾性分析1例15岁男性青少年喉鳞状细胞癌患者的临床资料并复习相关文献。结果患者,男,15岁,因声嘶1年行纤维喉镜下声带肿物切除术,术后病理检查为鳞状上皮乳头状瘤伴中度不典型增生,两个月后给予质子泵抑制剂治疗40天疗效不佳,入院行CO2激光肿瘤切除术,病理诊断为喉鳞状细胞癌(声门型T1bN0M0),再次行支撑喉镜下CO2激光声门癌扩大切除术。术后4.5个月时由于喉狭窄呼吸困难行声门扩大术,术后呼吸困难明显改善,随访14个月患者未出现复发和喉狭窄,嗓音较术前改善。结论青少年乳头状瘤有发生恶变的可能;对肿瘤局限于声门者可采用支撑喉镜下CO2激光切除术。
关键词
青少年;喉乳头状瘤;喉癌;激光;喉狭窄
基金项目(Foundation):
作者
葛平江;梅平;程秋惠;盛晓丽;张思毅;陈少华;
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