下咽滑膜肉瘤一例诊治体会

朱梅;李革临;候倩;白雪;俞方;李莉;

1:首都医科大学附属北京友谊医院耳鼻咽喉-头颈外科

摘要
目的探讨原发于下咽部的滑膜肉瘤的诊断及治疗要点。方法回顾性分析一例下咽滑膜肉瘤患者的临床资料、病理诊断、治疗方式及疗效,并复习相关文献。结果患者女,14岁,临床表现为咽部异物感,言语含糊,吞咽梗阻易呛咳。查体可见肿物位于下咽后壁偏右侧,表面光滑,呈分叶状,实性,质软,色灰白,蒂广。颈部MRI示下咽部占位性病变,呈等T1稍长T2信号影,增强扫描后明显强化。经右侧梨状窝入路行肿物切除术,术中见肿物有包膜,与周围组织界限清楚,行肿物切除术。显微镜下见肿瘤组织由上皮细胞和梭形细胞组成,核分裂不易见,基因检测见其具有特征性染色体异位T(X;18)(P11.2;Q11.2)。病理诊断为滑膜肉瘤(双相型)。术后辅以放疗,一年半后复查未见肿瘤复发。结论下咽滑膜肉瘤较罕见,主要依靠病检确诊,治疗方式以手术为主,辅以放化疗。
关键词
滑膜肉瘤;下咽部;治疗
基金项目(Foundation):
作者
朱梅;李革临;候倩;白雪;俞方;李莉;
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