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鼓膜穿孔对中耳传音功能影响的实验观察

Experimental Studies on the Effects of the Tympanic Membrane Perforation on Middle Ear Transmission

张秀玲;佘万东;赵青;陈金湘;张淑仪;戴艳红;

1:东南大学医学院附属江阴医院耳鼻咽喉科

2:南京大学医学院附属鼓楼医院耳鼻咽喉头颈外科

3:南京大学声学研究所

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摘要

目的通过观察豚鼠鼓膜不同位点的振动情况及穿孔前后锤骨柄不同位点的振动改变情况,初步探讨鼓膜穿孔对中耳传音机制的影响。方法采用6只新鲜豚鼠颞骨标本,采用直径1.1mm的静脉留置针穿刺左耳鼓膜前下方和/或右耳鼓膜后下方并旋转一周造孔;于鼓膜造孔前后给予强度为90dB SPL、0.58kHz共14个频率的声刺激,利用激光多普勒振动仪检测系统测量完整鼓膜不同位点的振动速度及不同位置鼓膜穿孔前后锤骨柄不同位点的振动速度。完整鼓膜上六个测量位点分别为锤骨柄上的脐部、锤骨中部、短突及鼓膜紧张部上锤骨柄内侧、外侧、下部的三个点。结果完整鼓膜所测六个位点中位于脐部下方的位点振动速度最大。鼓膜穿孔前后脐部振动的频率响应曲线的形状基本相似,1.5kHz以下频率范围内振动损失较明显,1.5kHz以上频率范围内振动损失减轻甚至增加。鼓膜后下方穿孔后0.5kHz频率处脐部振动损失最大,损失值为7dB。1.5kHz以下频率范围内鼓膜后下方穿孔引起的脐部振动损失比前下方穿孔大,但差异无统计学意义。在所测频率范围内锤骨短突与鼓膜脐部振动速度之比的均值均为0.5,鼓膜穿孔对这一比值未造成明显影响,不同部位鼓膜穿孔的影响也无统计学差异。结论鼓膜穿孔对鼓膜振动所造成的损失有频率依赖性,频率越低损失越严重。不同位置的鼓膜小穿孔对其传音功能的影响无统计学差异。

关键词

激光多普勒振动仪;鼓膜;穿孔;中耳;传音

基金项目(Foundation):

南京市医学科技发展项目(项目编号YKK08054)

作者

张秀玲;佘万东;赵青;陈金湘;张淑仪;戴艳红;

参考文献

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