突发性聋的遗传学研究进展

侯志强;王秋菊;

1:中国人民解放军总医院解放军耳鼻咽喉研究所耳内科

2:山东大学附属省立医院耳鼻咽喉头颈外科

3:山东省临床医学研究院眼耳鼻喉科学研究所

摘要
<正>突发性聋(sudden sensorineural hearing loss,SSNHL)是指突然发生的,可在数分钟、数小时或3天以内,原因不明的感音神经性听力损失,至少在相连的2个频率听力下降20dB以上[1]。患者除了听力损失之外,常伴发耳鸣、眩晕、耳胀满感等症状。有关其病因虽然已有血管因素、病毒感染、自身免疫性疾病、膜迷路积水等多种假说[2],但至今仍不能明确其病因及病理机制。最近的一些研究表明突聋的发病可能与遗传因素密切相关,先天性的血管因素异常、氧化应激反
关键词
基金项目(Foundation):
国家自然基金重点项目(30830104);国家自然基金重大国际合作项目(81120108009);; 全军“十二五”重点项目(BWS11J026)联合资助
作者
侯志强;王秋菊;
参考文献

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侯志强王秋菊