盐皮质激素受体对糖皮质激素的影响及其在自身免疫性内耳疾病中的作用

后婕;戴艳红;佘万东;

1:南京大学医学院附属鼓楼医院耳鼻咽喉科

摘要
<正>糖皮质激素(glucocorticoid,GC)按其作用时长可分为三种类型:短效的氢化可的松和可的松,中效的强的松、甲强龙及长效的地塞米松和倍他米松等。在用激素治疗炎性疾病时,不同个体对GC的反应并不完全一致:有些患者对GC治疗敏感,而有些患者表现为对GC的敏感性下降,甚至抵抗。由于体内影响GC发挥作用的因素很多,因此,形成GC抵抗的具体机制至今仍未被完全阐明。GC主
关键词
基金项目(Foundation):
国家自然基金面上项目(81271074);; 江苏省“六大人才高峰”项目(2009);; 南京市国际联合研究项目(2012sd311038);; 南京市医学科技发展项目(YKK13054)联合资助
作者
后婕;戴艳红;佘万东;
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后婕戴艳红佘万东