听神经病谱系障碍患者与正常听力者的耳蜗神经及面神经影像学比较

Differences in Cochlear Nerve and Facial Nerve Dimensions between Auditory Neuropathy Spectrum Disorder Patients and Normal Hearing Adults

彭利艳;肖云飞;毛忠瑶;陈请国;周良强;崔永华;廖波;张平;刘爱国;

1:华中科技大学同济医学院附属同济医院耳鼻咽喉头颈外科

2:华中科技大学同济医学院附属同济医院放射科

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摘要

目的比较听神经病谱系障碍(ANSD)患者和正常听力者的内听道段耳蜗神经及面神经的直径和面积之间的差异。方法以2009年1月2011年12月间华中科技大学附属同济医院耳鼻咽喉科确诊的11例ANSD的患者作为ANSD组,12例正常听力成人作为对照组,采用3DFIESTA序列的斜矢状位核磁共振成像技术分别测量两组对象内听道段耳蜗神经、面神经的直径和面积,比较两组间的差异。结果 ANSD组耳蜗神经的最短直径(0.33±0.06mm)明显小于对照组(0.79±0.08mm),耳蜗神经的最长直径(0.52±0.07mm)小于对照组(1.00±0.08mm),耳蜗神经的横截面积(0.22±0.04mm2)也明显小于对照组(0.70±0.10mm2),差异均有统计学意义(均为P<0.001);而ANSD组的面神经最大直径、最小直径和面积与正常对照组接近,差异无统计学意义(P>0.05)。结论 ANSD患者的耳蜗神经明显较正常听力成人细小。

关键词

耳蜗神经;面神经;核磁共振;听神经病谱系障碍

基金项目(Foundation):

国家自然科学基金项目(82171072)

作者

彭利艳;肖云飞;毛忠瑶;陈请国;周良强;崔永华;廖波;张平;刘爱国;

参考文献

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