聚乙二醇-b-聚(ε-聚己内酯)在内耳给药中的应用研究进展

李煜;戴春富;

1:复旦大学附属眼耳鼻喉科医院耳鼻咽喉头颈外科

摘要
<正>内耳给药是治疗梅尼埃病、突发性聋等内耳疾病的常用治疗手段,该技术主要是利用某些药物能渗透圆窗及卵圆窗的特点,或者直接运用手术的方法,使药物不经过血-内耳屏障直达内耳组织细胞中,从而对疾病进行治疗[1]。内耳局部用药有着全身用药无法比拟的优点,如药物目的性强,可直接进入内耳,淋巴液中药物浓度高,全身不良反应少等[2]。目前如何有效、精确、定量给药是内耳局部给药的难点。内耳给药技术与纳米技术的结合,在内
关键词
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作者
李煜;戴春富;
参考文献

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李煜戴春富