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突发性聋患者血小板平均体积检测结果分析

The Relationship of Mean Platelet Volume and Sudden Sensorineural Hearing Loss

郑雪松;后农生;郝锐;

1:北华大学附属医院耳鼻咽喉科

2:北华大学附属医院感染科

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摘要

目的分析突发性聋患者血小板平均体积(mean platelet volume,MPV)变化,初步探讨突发性聋的可能病因。方法以40例(40耳)突发性聋患者为研究对象(突聋组),其中轻度-中重度组(听力损失2570dB)15例(耳),重度-极重度组(听力损失≥71dB)25例(耳),另选择30例健康成人为对照组,比较两组外周血中血小板计数(PLT)、血小板平均体积(MPV)、血小板分布宽度(PDW)的水平。结果突聋组血小板计数为212.0±47.9×109/L,对照组为237.8±46.2×109/L,突聋组低于对照组,差异有统计学意义(P<0.05);突聋组MPV为10.9±0.8fL,对照组为10.3±0.8fL,突聋组高于对照组,差异有统计学意义(P<0.05);突聋组PDW为12.9%±2.0%,对照组为12.0%±1.3%,突聋组高于对照组,差异有统计学意义(P<0.05)。突聋组中轻度-中重度组MPV为11.0±1.1fL,重度-极重度组MPV为10.8±1.0fL,两组比较差异无统计学意义(P>0.05),两组MPV分别与对照组比较,差异均有统计学意义(P<0.05)。结论 MPV是血栓性疾病发生的独立危险因素,突发性聋患者MPV升高可能与内听道血管缺血或血栓事件有关。

关键词

血小板平均体积;突发性聋;血栓性疾病

基金项目(Foundation):

作者

郑雪松;后农生;郝锐;

参考文献

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