影响声带任克水肿程度的常见因素分析

Common Factors Associated with Severity of Reinke's Edema

申金霞;余力生;

1:北京大学人民医院耳鼻咽喉头颈外科

摘要

目的探讨影响声带任克水肿(Reinke’s edema)严重程度的常见因素。方法对85例声带任克水肿患者按病变程度分为I度19例,II度49例,III度17例,分别对不同程度组患者的吸烟、嗓音滥用、喉咽反流的关系进行分析。结果 85例中,喉咽反流阴性67例,阳性18例;43例有嗓音滥用,42例无嗓音滥用;66例有吸烟史,19例无吸烟史,烟龄≤25年25人,>25年41人。单项有序分类变量秩和检验及有序多分类logistic回归模型分析显示,烟龄超过25年(P<0.001)、喉咽反流(P<0.01)、嗓音滥用(P<0.01)与声带任克水肿分度有关。所有患者均经全麻支撑喉镜显微镜下行声带外侧微瓣术,术后随访一年以上,7例复发。结论吸烟、喉咽反流、嗓音滥用与声带任克水肿分度及复发有关,其中烟龄影响较大,烟龄越长,水肿程度越重。

关键词

任克水肿;声带;吸烟;喉咽反流;嗓音滥用

基金项目(Foundation):

作者

申金霞;余力生;

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申金霞余力生