慢性噪声暴露对大鼠听皮层及海马脑区胰岛素样生长因子-1表达的影响
Effects of Chronic Noise Exposure on the Expression of IGF-1 in Both the Auditory Cortex and the Hippocampus of Rats
杨希林;廖华;陈抗松;解为全;杨琨;朱占永;
1:武汉大学人民医院耳鼻咽喉-头颈外科
2:武汉大学人民医院整形外科
摘要关键词基金项目(Foundation):作者参考文献1 Ising H,Kruppa B.Health effects caused by noise:evidence in the literature from the past 25years[J].Noise Health,2004,6:5.
2 Bibollet-Bahena O,Cui QL,Almazan G.The insulin-like growth factor-1axis and its potential as a therapeutic target in central nervous system(CNS)disorders[J].Cent Nerv Syst Agents Med Chem,2009,9:95.
3 Fernandez AM,Torres-Aleman I.The many faces of insuin-like peptide signalling in the brain[J].Nat Rev Neurosci,2012,13:225.
4 Guan J,Mathai S,Liang H,et al.Insulin-like growth factor-1and its derivatives:potential pharmaceutical application for treating neurological conditions[J].Recent Pat CNS Drug Discov,2013,8:142.
5 Wibke S,Annalisa Z,Mirko J,et al.Noise-induced inner hair cell ribbon loss disturbs central arc mobilization:a novel molecular paradigm for understanding tinnitus[J].Mol Neurobiol,2013,47:261.
6 Coordes A,Grschel M,Ernst A,et al.Apoptotic cascades in the central auditory pathway after noise exposure[J].J Neurotrauma,2012,29:1 249.
7 Basta D,Tzschentke B,Ernst A.Noise-induced cell death in the mouse medial geniculate body and primary auditory cortex[J].Neurosci Lett,2005,381:199.
8 Godfrey DA,Kaltenbach JA,Chen K,et al.Amino acid concentrations in the hamster central auditory system and longterm effects of intense tone exposure[J].J Neurosci Res,2012,90:2 214.
9 Uran SL,Aon-Bertolino ML,Caceres LG,et al.Rat hippocampal alterations could underlie behavioral abnormalities induced by exposure to moderate noise levels[J].Brain Res,2012,1 471:1.
10 Cui B,Zhu L,She X,et al.Chronic noise exposure causes persistence of tau hyperphosphorylation and formation of NFT tau in the rat hippocampus and prefrontal cortex[J].Exp Neurol,2012,238:122.
11 Cheng B,Maffi SK,Martinez AA,et al.Insulin-like growth factor-I mediates neuroprotection in proteasome inhibition-induced cytotoxicity in SH-SY5Ycells[J].Mol Cell Neurosci,2011,47:181.
12 Gleichmann M,Weller M,Schulz JB.Insulin-like growth factor-1-mediated protection from neuronal apoptosis is linked tophosphorylation of the pro-apoptotic protein BAD but not to inhibition of cytochrome c translocation in rat cerebellar neurons[J].Neurosci Lett,2000,282:69.
13 Maya-Vetencourt JF,Baroncelli L,Viegi A,et al.IGF-1restores visual cortex plasticity in adult life by reducing local GABA levels[J].Neural Plast,2012.doi:10.1155/2012/250421.
14 Dupraz S,Grassi D,Karnas D,et al.The insulin-like growth factor 1receptor is essential for axonal regeneration in adult central nervous system neurons[J].PLoS One,2013,8:e54462.