脊柱模式生物斑马鱼用于内耳科学领域研究的进展

周金章;龙孝斌;

1:南方医科大学珠江医院耳鼻咽喉头颈外科

摘要
<正>斑马鱼(danio rerio)属鲤科、辐鳍亚纲、短担尼鱼属,原产于印度等地水域。斑马鱼体型纤细,成鱼体长约35cm,寿命25cm,寿命23年;其胚胎及早期幼鱼通体透明,生殖周期短、繁殖能力强,且基因与人类基因约87%相似。鉴于斑马鱼以上生物学特性,耳科学研究者亦采用斑马鱼模型探讨毛细胞再生、遗传性聋机制、耳毒性和抗耳毒性药物筛查等。为此,本文对近年来斑马鱼模型用于内耳科学领域的研究现状及进展综述如下。
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周金章;龙孝斌;
参考文献

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周金章龙孝斌