阻塞性睡眠呼吸暂停低通气综合征和单纯鼾症者鼾声的基频及共振峰分析

Analysis of Fundamental Frequency and Formants of Snoring Sound from Patients with Obstructive Sleep Apnea-Hypopnea Syndrome and Simple Snoring

彭好;许辉杰;黄魏宁;杨弋;贺宇霞;李传颖;

1:卫生部北京医院耳鼻咽喉科

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摘要

目的研究阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OS-AHS)和单纯鼾症(simple snoring,SS)者鼾声的基频和共振峰特点,探讨其可能的临床应用价值。方法对50例OSAHS患者(OSAHS组,轻度16例,中度15例,重度19例)和20例SS者(单纯鼾症组)行同步多导睡眠监测和鼾声监测,截取每例患者不同睡眠时段的10次鼾声,使用Prrat语音分析软件对鼾声的基频和共振峰进行分析。结果 SS组有明显的基频,在100Hz段以下分布聚集,而OSAHS组鼾声基频无规律;SS组鼾声的第一共振峰值(F1)明显小于OSAHS组;OSAHS组中,重度组F1最高,轻度组最低,且各组间两两比较差异均有统计学意义。结论 OSAHS患者与SS者的鼾声基频和共振峰频率特别是F1有明显差别,F1值的大小与OSAHS的严重程度有一定关系,鼾声的基频及共振峰值有助于OSAHS与SS的区分以及OSAHS严重程度的大致判断;根据SS者鼾声的基频可能有助于鼾声来源的鉴别。

关键词

阻塞性睡眠呼吸暂停低通气综合征;单纯鼾症;鼾声;基频;共振峰

基金项目(Foundation):

国家自然科学基金面上课题资助项目(61271410)

作者

彭好;许辉杰;黄魏宁;杨弋;贺宇霞;李传颖;

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