线粒体MT-RNR1基因突变与药物性聋

曾云;冯大飞;张磊;姜丹;

1:深圳华大基因研究院

摘要
<正>大多数线粒体基因突变会引起母系遗传性疾病,而线粒体MT-RNR1基因突变主要引起药物性非综合征型母系遗传性聋,其导致的耳聋为双侧、程度不等且与氨基糖苷类药物的使用有关。线粒体基因突变导致的药物性聋的防治关键在"防",通过人为干预,可以有效的减少药物性聋的发生。目前国际上对于线粒体突变导致的药物性聋的报导逐渐
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曾云;冯大飞;张磊;姜丹;
参考文献

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曾云冯大飞张磊姜丹