症状性巨细胞病毒感染婴幼儿的听力损失及治疗探讨

Hearing Loss and Its Management in Infants with Symptomatic Cytomegalovirus Infection

刘世琳;陈敏;刘卫一;姜苏敏;王桂香;张亚梅;张莉;焦雪梅;刘薇;胡艳;潘岳松;

1:首都医科大学北京儿童医院耳鼻喉科

摘要
目的观察症状性巨细胞病毒感染患儿的听力损失程度及恢复情况,探讨有效的干预措施。方法对2007年6月至2009年6月住院治疗的55例症状性巨细胞病毒感染患儿进行ABR测试,比较抗病毒治疗前后ABR阈值变化及后期语言发育情况。结果 55例中双耳ABR阈值正常37例,异常18例,其中,单耳异常11例、双耳异常7例,听力受损率占总例数的32.73%(18/55),中或重度听力损失率16.36%(9/55)。治疗后复测ABR 7例,阈值恢复正常或改善。初次电话随访23例,其中,听力语言发育好16例,一般4例,发育差2例,死亡1例。第二次随访21例,17例语言发育与同龄儿无差异,正常入托或上学前班,3例语言发育较同龄儿差,1例死亡。结论症状性巨细胞病毒感染的婴幼儿听力损失发生率较高,抗病毒治疗对听力损失的恢复有一定效果。
关键词
婴幼儿;症状性;巨细胞病毒感染;听力损失
基金项目(Foundation):
作者
刘世琳;陈敏;刘卫一;姜苏敏;王桂香;张亚梅;张莉;焦雪梅;刘薇;胡艳;潘岳松;
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