未折叠蛋白反应在强噪声致豚鼠耳蜗细胞损伤过程中的作用
Participation of the Unfolded Protein Response in the Guinea Pig Cochlea Cell Damage after Intense Noise Exposure
薛秋红;陈小林;龚树生;谢静;陈佳;何坚;
1:武汉科技大学附属天佑医院耳鼻咽喉科
2:首都医科大学附属北京同仁医院耳鼻咽喉头颈外科
摘要关键词基金项目(Foundation):作者参考文献1 Hayashi T,Saito A,Okuno S,et al.Induction of GRP78 byischemic preconditioning reduces endoplasmic reticulum stressand prevents delayed neuronal cell death[J].J Cereb BloodFlow Metab,2003,23:949.
2 Hoozemans JJ,Veerhuis R,Van Haastert ES,et al.The unfol-ded protein response is activated in Alzhei mer/s disease[J].Acta Neuropathol,2005,110:165.
3 Hayashi T,Saito A,Okuno S,et al.Induction of GRP78 byischemic reconditioning reduces endoplasmic reticulum stressand prevents delayed neuronal cell death[J].Cereb Blood FlowMetab,2003,23:949.
4 Hu BH,Nicotera T,Henderson D.Involvement of apoptosisin progression of cochlear lesion following exposure to intensenoise[J].Hear Res,2002,166:62.
5薛秋红,陈佳,龚树生,等.Caspase-12在强噪声诱导下豚鼠耳蜗细胞凋亡中的作用[J].中华耳鼻咽喉头颈外科杂志,2009,44:154.