IL-6表达与腺样体肥大伴分泌性中耳炎发病的关系

张爱英;张勋;苏金柱;

1:河北省儿童医院耳鼻咽喉科

2:河北医科大学第三医院耳鼻咽喉科

摘要
目的检测白细胞介素-6(IL-6)在单纯腺样体肥大及腺样体肥大伴分泌性中耳炎(otitis mediawith effusion,OME)患儿的腺样体组织及血清中的表达,探讨IL-6与OME发病的关系。方法单纯腺样体肥大组患儿20例(男12例,女8例),腺样体肥大伴OME组患儿20例(男11例,女9例),分别检测两组患儿腺样体组织及血清中IL-6的表达并进行比较。结果腺样体肥大伴分泌性中耳炎组腺样体组织中IL-6的表达明显高于单纯腺样体肥大组(P<0.05),两组患儿血清中IL-6的表达差异无统计学意义(P>0.05)。结论腺样体局部IL-6的高表达可能与分泌性中耳炎发病有关。
关键词
分泌性中耳炎;腺样体肥大;白细胞介素-6
基金项目(Foundation):
作者
张爱英;张勋;苏金柱;
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