声带白斑124例临床及病理分析

Clinical and Pathological Analysis for 124 Cases of Vocal Cord Leukoplakia

杨庆文;徐文;叶京英;王军;马丽晶;王小轶;魏洪政;

1:首都医科大学附属北京同仁医院耳鼻咽喉头颈外科中心

摘要
目的探讨声带白斑的临床表现和病理特征及相关因素。方法回顾性分析2006年1月至2008年12月收治的124例声带白斑患者的临床资料,患者均于全身麻醉下行显微支撑喉镜下声带白斑切除术,术后切除的病变组织送病理检查。结果 124例声带白斑患者中,男120例,女4例;年龄29~84岁,平均49.65±10.13岁;有长期吸烟史者89例(71.77%,89/124),长期饮酒者67例(54.03%,67/124);双侧声带前中部病变75例(60.48%,75/124),单侧声带前中部病变29例(23.38%,29/124);病理检查显示:黏膜慢性炎症10例(8.06%),鳞状上皮增生88例(70.96%),黏膜轻度异型增生6例(4.84%),中度异型增生5例(4.03%),重度异型增生5例(4.03%),原位癌6例(4.84%),浸润癌4例(3.23%)。结论声带白斑以男性多见,长期烟酒嗜好可能是主要病因之一,其病变性质以病理诊断为依据,对病理检查提示有异型增生者需密切随诊观察。
关键词
声带白斑;癌前病变;病理诊断
基金项目(Foundation):
北京市卫生系统高层次卫生技术人才骨干基金(2009-3-33)
作者
杨庆文;徐文;叶京英;王军;马丽晶;王小轶;魏洪政;
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