分泌性中耳炎模型大鼠中耳黏膜中上皮钠通道mRNA的表达及其意义
李祥翠;张奕;李吉平;王家东;
1:上海交通大学医学院附属仁济医院耳鼻咽喉-头颈外科
2:上海交通大学(医学院)耳鼻咽喉科研究所
1 Portier F,Kania R,Planès C,et al.Enhanced sodium absorp-tion in middle ear epithelial cells cultured at air-liquid inter-face[J].Acta.Otolaryngol,2005,125:16.
2 Guidot DM,Folkesson HG,Jain L,et al.Integrating acutelung injury and regulation of alveolar fluid clearance[J].Am JPhysiol Lung Cell Mol Physiol,2006,291:L301.
3 Cho JG,Lee ES,Woo JS,et al.Expressions of cyclooxygen-ase 1 and 2 in endotoxin-induced otitis media with effusioninthe rat[J].Int J Pediatr Otorhinolaryngol,2007,71:101.
4 Rochelle LG,Li DC,Ye H,et al.Distribution of ion transportmRNAs throughout murine nose and lung[J].Am J PhysiolLung Cell Mol Physiol,2000,279:14.
5 Song Y,Namkung W,Nielson DW,et al.Airway surfaceliq-uid depth measuredin ex vivo fragments of pig and human tra-chea:dependence on Na+and Cl-channel function[J].AmJPhysiol Lung Cell Mol Physiol,2009,297:L1 131.
6 Choi JY,Son EJ,Ki mJL,et al.ENaC-and CFTR-depend-ent ion and fluid transport in human middle ear epithelial cells[J].Hear Res,2006,211:26.
7 Choi JY,Choi YS,Ki mSJ,et al.Interleukin-1beta suppres-ses epithelial sodium channel beta-subunit expression andENaC-dependent fluid absorptionin human middle ear epithe-lial cells[J].Eur J Pharmacol,2007,567:19.
8 Son EJ,Ki mSH,Park HY,et al.Activation of epithelial so-diumchannel in human middle ear epithelial cells by dexam-ethasone[J].Eur J Pharmacol,2009,602:383.
9 Portier F,Van den Abbeele T,Lecain E,et al.Oxygen modu-lates Na+absorptionin middle ear epithelium[J].AmJ Phys-iol,1999,276:C312.
10 Li JP,Kania R,Eric L,et al.In vivo demonstration of theabsorptive function of the middle ear epithelium[J].HearingResearch,2005,210:1.
11李吉平,金晓杰,王家东,等.钠离子浓度变化对大鼠中耳液体吸收功能影响的研究[J].听力学及言语疾病杂志,2008,16:411.
12 Yellon RF,Leonard G,Marucha PT,et al.Characterizationof cytokines present in middle ear effusions[J].Laryngo-scope,1991,101:165.
13 Song JJ,Kown SK,Ki m EJ,et al.Mucosal expression ofENaC and AQP in experi mental otitis media induced by Eu-stachian tube obstruction[J].Int J Pediatr Otorhinolaryngol,2009,73:1 589.