耳蜗传入通路在耳蜗信号编码中的意义

陈熹;余力生;李兴启;

1:北京大学人民医院耳鼻咽喉科

2:解放军总医院耳鼻咽喉科研究所

摘要
<正>随着人工耳蜗技术的广泛开展,人们试图用电刺激产生的听觉现象来模拟听觉生理过程,这也是目前在毛细胞损伤后重建听觉的唯一有效途径。事实上,听神经对声刺激和电刺激的反应性质有很多差异,即电刺激产生的听觉存在着许多局限性,如频率选择性差、动态范围狭窄、电刺激的空间分布比较弥散、时间锁相特性差等,提示听觉系统对于声刺激,可能在耳蜗水平就存在一定的信号编码处理功能。目前,关注耳蜗外毛细胞的研究较多,外毛细胞对内毛细胞有驱动作用,对听觉传入通路的灵敏度有调节作用。而在耳蜗听觉信
关键词
基金项目(Foundation):
国家自然基金(81070780);; 首都医学发展基金(2009-1015)联合资助
作者
陈熹;余力生;李兴启;
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陈熹余力生李兴启