鼓室注入庆大霉素治疗梅尼埃病的研究进展

高帆;蒋子栋;

1:首都儿科研究所附属儿童医院耳鼻喉科

2:中国医学科学院北京协和医科大学北京协和医院耳鼻喉科

摘要
<正>梅尼埃病(Meniere’s disease,MD)是一种特发性的内耳疾病,典型症状包括反复发作的眩晕、波动性听力下降、耳鸣及耳胀满感等,其基本病理改变为膜迷路积水,积水发生的顺序为耳蜗、球囊、椭圆囊、半规管。其发病机制主要是内淋巴产生过多和/或吸收障碍。内淋巴由耳蜗血管纹及前庭暗细胞产生,通过局部环流及纵流方式达内淋巴囊而被吸收,来维持其容量的恒定。因此,破坏前庭系统感觉细胞,减少中枢兴奋性传递,破坏前庭系统的暗细胞功能以减少内淋巴
关键词
基金项目(Foundation):
国家人事部归国启动基金择优项目;; 中国医学科学院与日本学术振兴会合作项目
作者
高帆;蒋子栋;
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高帆蒋子栋