组织工程PHBHH多孔材料喉支架的制备与细胞相容性研究
Fabrication of Larynx-Shape Porous PHBHH for Cartilage Tissue Engineering and the Cytocompatibility with Chondrocytes
孙安科;胡平;李万同;孟庆延;陈伟;唐维维;
1:沈阳军区总医院耳鼻咽喉科
2:清华大学化学工程系
3:沈阳军区总医院整形科
4:沈阳军区总医院烧伤科
摘要关键词基金项目(Foundation):作者参考文献1孙安科,陈文弦,崔鹏程,等.同种异体工程软骨的构建和修复甲状软骨缺损的实验研究[J].中华耳鼻咽喉科杂志,2001,36:278.
2孙安科,裴国献,周国平,等.改良以聚羟基乙酸为支架同种异体组织工程化塑形软骨的构建[J].第一军医大学学报,2002,22:996.
3 Mikos AG,Sarakinos G,Leite SM,et al.Laminated three-di-mensional biodegradable foams for ues in tissue engineering[J].Biomaterials,1993,14:323.
4 Zhang R,Ma PX.Poly(alpha-hydroxylacids)hydroxyaptiteporous composites for bone-tissue engineering:Preparationand morphology[J].J Biomed Mater Res,1999,44:446.
5詹兴旺,姜艳.软骨组织工程化用细胞支架生物材料的研究进展[J].中国矫形外科杂志,2010,18:1 530.
6 Zhao K,Deng Y,Chen J,et al.Polyhydroxyalkanoate(PHA)scaffolds with good mechanicalproperties and biocompatibility[J].Biomaterials,2003,24:1 041.
7 Kose GT,Korkusuz F,Ozkul A,et al.Tissue engineered car-tilage on collagen and PHBV matrices[J].Biomaterials,2005,26:5 187.
8 Deng Y,Lin X,Zheng Z,et al.Poly(hydroxybutyrate-co-β-hydrobexanoatey)promoted production of extracellular ma-trix of articular cartilage chondrocytes in vitro[J].Biomateri-als,2003,24:4 273.
9 Tani G,Usui N,Kamiyama M,et al.In vitro construction ofscaffold-free cylindrical cartilage using cell sheet-based tis-sue engineering[J].Pediatr Surg Int,2010,26:179.
10 Kim DY,Pvun J,Choi JW,et al.Tissue-engineered al-lograft tracheal cartilage using fibrin/hyaluronan compositegel and its in vivo implantation[J].Laryngoscope,2010,120:30.