人工耳蜗植入者EABR与ECAP分析

The Study of EABR and ECAP in Cochlear Implantation

葛晓华;王林娥;张道行;

1:首都医科大学附属北京友谊医院耳鼻咽喉科

摘要

目的探讨听觉电诱发电位对人工耳蜗植入者的电听觉传导功能客观评价的意义。方法对14例人工耳蜗植入者行电诱发听性脑干反应(electrically evoked audiotory brainstem responses,EABR)和电诱发听神经复合动作电位(electrically evoked compound action potential,ECAP)检查,根据第1、10、22号电极ECAP波形的检出与否将其分成A(1、10、22号电极ECAP均检出)、B(1、10、22号三个电极中有一个及以上ECAP未检出)两组,检测A组和B组患者的EABR阈值、波Ⅲ、Ⅴ潜伏期、Ⅲ-Ⅴ波间期并对其结果进行比较。结果刺激脉宽分别为25、50、75、100、125μs时,22号电极的EABR阈值B组高于A组,差异有显著统计学意义(P<0.001);刺激脉宽为50μs时:1号和10号电极的EABR阈值B组高于A组,差异有显著统计学意义(P<0.001)。A、B两组患者22、10、1号电极EABR波Ⅲ、Ⅴ潜伏期和Ⅲ-Ⅴ波间期之间的差异无统计学意义(P>0.05)。结论 ECAP波形较好者的EABR阈值较ECAP波形较差者的EABR阈值低。EABR波Ⅲ、Ⅴ潜伏期、Ⅲ-Ⅴ波间期与ECAP波形引出与否无明显相关性,ECAP灵敏性高而EABR稳定性好。

关键词

电诱发听性脑干反应;电诱发听神经复合动作电位;神经反应遥测

基金项目(Foundation):

作者

葛晓华;王林娥;张道行;

参考文献

1Nikolopoulos TP,Dyar D,Gibbin KP.Assessing candidate chil-dren for cochlear i mplantation with the Nottingham Children's I mplant Profile(NChIP):The first200children[J].Int J Pe-diatr Otorhinolaryngol,2004,68:127.

2王硕,赵啸天,陈雪清,等.神经反应遥测技术在人工耳蜗手术中的应用[J].中国听力语言康复科学杂志,2004,1:14.

3王硕,韩德民.神经反应遥测技术在多导人工耳蜗病人听觉评估中的应用[J].国外医学-耳鼻咽喉科学分册,2002,26:338.

4Brown CJ,Hughes ML,Luk B,et al.The relationship be-tween EAP and EABR thresholds and levels used to program the nucleus24speech processor:Data from adults[J].Ear-Hear,2000,21:151.

5Shallop JK,Facer GW,Peterson A.Neural response teleme-try with the nucleus CI24M cochlear i mplant[J].Laryngo-scope,1999,109:1755.

6Kileny PR,Zwolan TA,Zi mmerman-Phillips S,et al.Electri-cally evoked auditory brain-stem response in pediatric pa-tients with cochleari mplants[J].Arch Otolaryngol Head Neck Surg,1994,120:1083.

7Abbas P,Brown CJ,Shallop JK,et al.Summary of result using the nucleus CI24Mi mplant to record the electrically evoked compound action potential[J].Ear Hear,1999,20:45.

8陈雪清,王硕,韩德民.参数改变对神经反应遥测波形的影响[J].听力学及言语疾病杂志,2002,10:67.

9Aubert LR,Clarke GP.Reliability and predictive value of the electrically evoked auditory brainstem responses[J].British Journal of Audiology,1994,28:121.

10Hay-Mc Cutcheon MJ,Brown CJ,Clay KS,et al.Compari-son of electrically evoked whole-nerve action potential and e-lectrically evoked auditory brainstem response thresholds in nucleus CI24Rcochleari mplant recipients[J].J Am Acad Au-diol,2002,13:416.

11Mason S.Electrophysiologic and objective monitoring of the cochlear i mplant during surgery:I mplementation,audit and outcomes[J].Int J Audiol,2004,43(Suppl1):S33.

12Kileny PR,Zwolan TA.Pre-perioperative,transtympanic electrically evoked auditory brainstem response in children[J].Int J Audiol,2004,43(Suppl1):S16.

13Gordon KA,Papsin BC,Harrison RV.Toward a battery of behavioral and objective measures to achieve opti mal cochlear i mplant sti mulation levels in children[J].Ear Hear,2004,25:447.

14Kubo T,Yamamoto K,Iwaki Y,et al.Significance of audi-tory evoked responses(EABRand P300)in cochlear i mplant subjects[J].Acta Otolaryngol,2001,121:257.

15张道行,张岩昆,田昊,等.人工耳蜗植入者EABR、NRT与ESR检测[J].听力学及言语疾病杂志,2005,13:310.

本文信息

PDF(544K)

本文关键词相关文章

电诱发听性脑干反应电诱发听神经复合动作电位神经反应遥测

本文作者相关文章

葛晓华王林娥张道行