地塞米松鼓室内灌注治疗突发性聋

赵远新;周晓娓;姚清华;谢雪颜;虞幼军;王跃建;

1:广东省佛山市第一人民医院耳鼻咽喉科

摘要
目的观察鼓室内灌注地塞米松治疗突发性聋的效果。方法 126例(151耳)突聋患者分为初始治疗组和挽救治疗组,初始治疗组再分为鼓室给药组(A组,42耳)和全身给药组(B组,34耳),挽救治疗组再分为鼓室给药组(C组,40耳)和全身给药组(D组,35耳),鼓室给药组鼓室灌注地塞米松,全身给药组静脉滴注地塞米松,治疗2周后复查听力,比较疗效。结果在初始治疗组中,A组37耳有效,5耳无效,总有效率88.1%(37/42);B组21耳有效,13耳无效,总有效率61.8%(21/34),A组疗效显著高于B组(P<0.05);在挽救治疗组中,C组23耳有效,17耳无效,总有效率57.5%(23/40);D组9耳有效,26耳无效,总有效率25.7%(9/35),C组疗效显著高于B组(P<0.05)。结论鼓室灌注地塞米松作为突发性聋的初始治疗和挽救治疗方法较静脉全身给药有更好的治疗效果。
关键词
鼓室灌注;地塞米松;突发性聋
基金项目(Foundation):
作者
赵远新;周晓娓;姚清华;谢雪颜;虞幼军;王跃建;
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