经咽鼓管鼓室内灌注地塞米松治疗突发性聋

Intratympanic Dexamethasone Perfusion via Eustachian Tube for Treatment of Sudden Sensorineural Hearing Loss

彭好;张秋颖;周金梅;宋海涛;黄魏宁;

1:卫生部北京医院耳鼻咽喉科

摘要

目的评价经咽鼓管途径鼓室内灌注地塞米松治疗突发性聋的安全性和疗效。方法将67例(67耳)突发性聋患者随机分为A组20例(20耳),单纯经咽鼓管鼓室内灌注地塞米松(5 mg/ml)0.6毫升/次;B组23例(23耳),常规全身治疗无效后再经咽鼓管鼓室内灌注地塞米松(5mg/ml)0.6毫升/次;C组24例(24耳),单纯常规全身治疗,比较三组治疗前后受损频率平均听阈变化及咽鼓管功能变化。结果A、B、C三组有效率分别为85.00%(17/20)、60.87%(14/23)、45.3%(11/24),三组伴随症状耳鸣、耳闷、眩晕都有一定缓解,没有出现中耳炎及耳闷、耳痛等感染症状,鼓室导抗图和咽鼓管吹张实验治疗前后没有明显变化。结论经咽鼓管途径鼓室内灌注地塞米松治疗突发性聋是安全和有效的,可在临床推广使用。

关键词

突发性聋;鼓室内灌注;咽鼓管;地塞米松

基金项目(Foundation):

作者

彭好;张秋颖;周金梅;宋海涛;黄魏宁;

参考文献

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突发性聋鼓室内灌注咽鼓管地塞米松

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