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听性稳态反应在新生儿听力评估中的应用

The Application of Auditory Steady-State Responses to the Neonates Hearing Evaluation

张云飞;许政敏;

1:复旦大学附属儿科医院耳鼻咽喉科

2:上海市儿童听力障碍诊治中心

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摘要

目的探讨听性稳态反应(auditory steady-state responses,ASSR)在新生儿听力评估中的准确性及应用价值。方法对30例(60耳)畸变产物耳声发射(distortion product otoacoustic emission,DPOAE)正常的新生儿和45例(78耳)DPOAE异常的新生儿进行ASSR与听性脑干反应(auditory brainstem response audiome-try,ABR)测试,比较ASSR与ABR阈值差异有无统计学意义,并进行两者反应阈的相关性分析。结果①DPOAE正常组:ASSR 250 Hz反应阈与ABR阈值差异有统计学意义(P<0.05),ASSR平均阈值及4 000 Hz反应阈与ABR阈值差异无统计学意义(P>0.05),ASSR的250、500、1 000 Hz反应阈与ABR阈值相关性不明显,但2 000、4 000 Hz反应阈与ABR阈值有明显的相关性;②DPOAE异常组:ASSR的2504 000 Hz阈值及平均阈值与ABR阈值差异均无统计学意义(P>0.05)。ASSR各频率反应阈与ABR阈值均有显著的相关性。结论ASSR可以比较准确地评估听力筛查正常新生儿的平均听阈和中、高频听阈以及听力筛查未通过新生儿的各频率听阈。

关键词

听性稳态反应;听性脑干反应;新生儿

基金项目(Foundation):

作者

张云飞;许政敏;

参考文献

1 Picton T,John M,Dimitrijevic A,et al.Human auditory steady-state responses[J].International Journal of Audiology,2003,42:177.

2 John MS,Brown DK,Muir PJ,et al.Recording auditorysteady-state responses in young infants[J].Ear and Hear-ing,2004,25:539.

3 Cone-Wesson B,Dowell RC,Tomlin D,et al.The auditorysteady-state response:comparisons with the auditory brain-stem response[J].J Am Acad Audiol,2002,13:173.

4 Ross B,Picton TW,Pantev C.Temporal integration in the hu-man auditory cortex as represented by the development of thesteady state magnetic field[J].Hear Res,2002,165:68.

5 Stapells DR,Herdman A,Small SA,et al.Current status ofthe auditory steady-state responses for estimating an infant's audiogram[M].In:Seewald RC,Bamford JM,eds.Asound foundation through early amplification.Basel:PhonakAG,2004.43~59.

6 Stapells DR.Threshold estimation by t he tone-evoked au-ditory brainstem response:A literature meta-analysis[J].Journal of Speech-Language Pathology and Audiology,2000,24:74.

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