女性慢性肾衰竭患者血液透析前后嗓音声学特征分析

The Effects of Hemodialysis on the Voicing Characteristics of Patients with Chronic Renal Failure

马清学;张道行;刘文虎;李革临;张东亮;刘韵;朱梅;

1:北京友谊医院耳鼻咽喉科

2:北京友谊医院血液净化中心

摘要
目的分析女性慢性肾衰竭(chronic renal failure,CRF)患者血液透析前后的嗓音声学特征。方法对28例女性CRF患者血液透析前后的嗓音进行声学分析,选取3秒平稳段持续长元音/a:/声信号作为分析样本,测试其基频(F0)、基频微扰(jitter)、振幅微扰(shi mmer)、最低基频(Flo)、最高基频(Fhi)、嗓音扰动指数(VTI)、软发声指数(SPI)、相对平均扰动(RAP)、噪谐比(NHR)和最大发声时间(MPT)。结果28例CRF患者血液透析后F0、Fhi、Flo及MPT较透析前增加,差异有统计学意义(P<0.05);其余各参数中除VTI外,均较血液透析前增高,但差异无统计学意义(P>0.05)。慢性肾衰患者病程长短与嗓音声学参数无相关性。血液透析前后间接喉镜检查声带无明显改变。结论CRF血液透析后的嗓音声学参数中基频、最高基频、最低基频以及最大发声时间明显增加,与患者主观感觉血液透析后音调提高相一致。
关键词
慢性肾衰竭;血液透析;嗓音声学分析
基金项目(Foundation):
作者
马清学;张道行;刘文虎;李革临;张东亮;刘韵;朱梅;
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