口服和鼓室内注射糖皮质激素治疗分泌性中耳炎的疗效观察

The Therapeutic Effects of Oral Administration and Intratympanic Injection of Glucocorticoid in the Treatment of Otitis Media with Effusion

周涵;陈智斌;王登元;徐霞;赵晓埝;邢光前;

1:南京医科大学第一附属医院耳鼻咽喉科

摘要
目的探讨口服和鼓室内注射糖皮质激素治疗分泌性中耳炎(otitis media with effusion,OME)的疗效。方法选择84例病程在8周之内的OME患者(8~56岁)为研究对象,在进行鼓室穿刺抽液及口服抗生素的基础上,随机分成A组,30例34耳,予小剂量短疗程口服泼尼松治疗;B组,30例32耳,予地塞米松鼓室内注射2~4次;C组,24例26耳,口服抗生素,鼓室穿刺抽液。疗程结束后随访3个月。结果A、B两组分别有70.6%和53.1%的患耳在一周内有不同程度好转。治疗一个月后,A、B、C三组的总有效率分别为88.2%(30/34耳)、90.6%(29/32耳)和69.2%(18/26耳);A组与B组总有效率比较差异无统计学意义(P>0.05),但A、B两组与C组总有效率比较差异有统计学意义(P<0.05)。结论口服或鼓室内注射糖皮质激素均为治疗OME的有效方法。
关键词
糖皮质激素;分泌性中耳炎;鼓室内注射
基金项目(Foundation):
作者
周涵;陈智斌;王登元;徐霞;赵晓埝;邢光前;
参考文献

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