强噪声暴露下豚鼠耳蜗螺旋神经节细胞凋亡及Caspase-3的表达
Apoptosis and Caspase-3 Expression of Sprial Ganglion Cell (SGC) in Guinea Pig Cochlea with Intense Noise
薛秋红;陈佳;龚树生;谢静;罗凌惠;
1:华中科技大学同济医学院附属协和医院耳鼻咽喉科
2:武汉科技大学附属医院耳鼻咽喉科
3:华中科技大学同济医学院附属协和医院耳鼻咽喉科
4:华中科技大学同济医学院附属协和医院耳鼻咽喉科
1Hu BH,Guo W,Wang PY,et al.Intense noise-induced apoptosisin haircells of guinea pigcochleae[J].Acta Otolaryngol,2000,120:19.
2Aage R,Moller L.Pure spiral ganglion cell loss in acoustic trauma[M].In Hearing,Its physiology and pathophysiology.San Diego:Aca-demic press,2001.404~407.
3AlamSA,Ikeda K,Oshima T,et al.Cisplatin-induced apoptotic cell deathin mongolian gerbil cochlea[J].Hear Res,2000,141:28.
4杨卫平,胡博华.不同强度噪声刺激后灰鼠耳蜗外毛细胞死亡方式观察[J].解放军医学杂志,2005,30:524.
5Nicotera TM,Hu BH,Henderson D.The caspase pathway in noise-induced apoptosis of the chinchilla cochlea[J].J Assoc Res Otolaryn-gol,2003,4:466.
6Laugwitz KL,Moretti A,Weig HJ,et al.Blocking Caspase-activated apoptosisimproves contractility in failing myocardium[J].Hum Gene Ther,2001,12:2051.
7Liu VP,Staecker H,Stupak H,et al.Caspaseinhibitors prevent cispla-tininduced apoptosis of auditory sensory cells[J].Neuroreport,1998,9:2609.