神经营养因子在听觉神经元保护中的作用
贾明辉;卢伟;秦兆冰;
1:郑州大学第一附属医院耳鼻咽喉头颈外科
2:郑州大学第一附属医院耳鼻咽喉头颈外科
3:郑州大学第一附属医院耳鼻咽喉头颈外科 郑州450052 温州医学院附属第一医院耳鼻咽喉科
4:郑州450052
1Shepherd RK,Roberts LA,Paolini,AG.Long-termsensorineural hearingloss induces functional changes in the rat auditory nerve[J].Neurosci,2004,20:3131.
2Chen X,Frisina RD,Bower WJ,et al.HSVamplicon-mediated neuro-trophins-3expression protects murine spiral ganglion neurons from cisplatin-induced damag[J].Mol Ther,2001,3:958.
3郭雨霁,李盛芳.神经营养因子家族及其受体的研究进展[J].神经解剖学杂志,2001,17:288.
4Zheng JL,Stewart RR,Gao WQ.Neurotrophin-4/5enhances survi-val of cultured spiral ganglion neurons and protectsthemfromcisplatin neurotoxicity[J].J Neurosci,1995,15:5079.
5Fritzsch B,Silos-Santiago I,Bianchi LM,et al.Effects of neurotro-phin and neurotrophin receptor disruption on the afferent inner ear in-nervation[J].Semin Cell Dev Biol,1997,8:277.
6Mueller KL,Jacques BE,Kelley MW.Fibroblast growthfactor signa-lingregulates pillar cell development inthe organ of corti[J].J Neu-rosci,2002,22:9368.
7Lefebvre PP,Malgrange B,Staecker H,et al.Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro[J].Neuroreport,1994,5:865.
8施宁华,张志坚,戴树宏.神经生长因子对内耳缺血再灌注毛细胞损伤的保护作用[J].中国临床康复,2003,7:4191.
9阮芳铭,王海明,高文元,等.神经生长因子减轻噪声性阈移的透射电镜观察[J].中华耳鼻咽喉科杂志,2000,35:267.
10邓志宏,王锦玲,邱建华,等.神经营养因子3基因转染对庆大霉素性耳聋保护作用的实验研究[J].临床耳鼻咽喉科杂志,2004,18:231.
11Shepherd RK,Coco A,Epp SB,et al.Chronic depolarisationenhances the trophic effects of BDNF in rescuing auditory neurons following a sensorineural hearingloss[J].Comp Neurol,2005,486:145.
12朱雅颖,戴春富,余洪猛,等.胶质细胞来源的神经营养因子对螺旋神经节神经元耳毒性损伤的保护作用[J].听力学及言语疾病杂志,2006,14:48.
13Gillespie LN,Clark GM,Marzella PL.Delayed neurotrophin treat-ment supports auditory neuronsurvival in deaf guinea pigs[J].Neuro-report,2004,15:1121.
14Richardson RT,O’Leary S,Wise A,et al.Asingle dose of neuro-trophin-3tothe cochlea surrounds spiral ganglion neurons and pro-vides trophic support[J].Hear Res,2005,204:37.
15Wise AK,Richardson R,HardmanJ,et al.Resproutingandsurvival of guinea pig cochlear neuronsinresponse tothe administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3[J].Comp Neurol,2005,487:147.
16Yamagata T,Miller JM,Ulfendahl M,et al.Delayed neurotrophictreat-ment preserves nerve survival and electrophysiological responsiveness in neomycin-deafened guinea pigs[J].J Neurosci Res,2004,78:75.
17Gillespie LN,Clark GM,Bartlett PF,et al.LIFis more potent than BDNFin promoting neurite outgrowth of mammalian auditory neurons in vitro[J].Neuroreport,2001,12:275.
18Ochs G,Penn RD,York M,et al.AphaseI/II trial of recombinant me-thionyl human brain derived neurotrophic factor administered byintrathe-cal infusion to patients with amyotrophic lateral sclerosis[J].Amyotroph Lateral Scler Other Motor Neuron Disord,2000,1:201.
19Stover T,Yagi M,Raphael Y.Transduction of the contralateral ear af-ter adenovirus-mediated cochlear gene transfer[J].Gene Ther,2000,7:377.
20Mansour-Robaey S,Clarke DB,Wang YC,et al.Effects of ocularin-jury and administration of brain-derived neurotrophic factor on sur-vival and regrowth of axotomized retinal ganglion cells[J].Proc Natl Acad Sci USA,1994,91:1632.