神经生长因子在豚鼠耳蜗中的分布及其意义
Expression and Significance of NGF in the Cochlea of Guinea Pigs
池君;张学渊;宋武战;石东文;
1:第三军医大学附属西南医院耳鼻咽喉科
2:第三军医大学附属西南医院耳鼻咽喉科
3:第三军医大学成都军区昆明总医院
4:第三军医大学疾病蛋白质组学重庆市市级重点实验室 (重庆400038)
摘要关键词基金项目(Foundation):作者参考文献1 Harada T,Harada C,Nakayama N,et al.Modification of glial-neu-ronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration[J].Neuron,2000,26:533.
2 Ghinelli E,Johansson J,Rios JD,et al.Presence and localization of neurotrophins and neurotrophin receptors in rat lacrimal gland[J].In-vest Ophthalmol Vis Sci,2003,44:3352.
3 Garcia M,Forster V,Hicks D,et al.Invivo expressionof neurotrophins and neurotrophin receptors is conservedin adult porcine retina in vitro[J].Invest Ophthalmol Vis Sci,2003,44:4532.
4 Muller Y,Duperray C,Carusl F,et al.Autocrine regulation of prolif-eration of cerebeliar granule neurons by nerve growthfactor[J].J Neu-rosci Res,1994,38:41.
5 Dai CF,Steyger PS,Wang ZM,et al.Expression of TrkAreceptors in the mammalianinner ear[J].Hearing Research,2004,187:1.
6 Pirvola U,Arumae U,Moshnyakov M,et al.Coordinated expression andfunction of neurotrophins and their receptors in the rat inner ear duringtarget innervation[J].Hear Res,1994,75:131.
7 Hantzopoulos PA,Suri C,Glass DJ,et al.The lowaffinity NGFrecep-tor,p75,can collaborate with each of the Trksto potentiate functional responses tothe neurotrophins[J].Neuron,1994,13:187.
8 Rosenthal A,Coeddel DV,Nguyen T,et al.Primary structure and bio-logical activity of novel human neurotrophic factor[J].Neuron,1990,4:767.
9 Shahrooz R,Justin Oh,Zhong LT,et al.Induction of apoptosis by the lowaffinity NGFreceptor[J].Science,1993,261:345.
10 Amendola T,Aloe L.Developmental expression of nerve growthfactor inthe eye of rats affected byinherited retinopathy:correlative aspects withretinal structural degeneration[J].ArchItal Biol,2002,140:81.
11 Hu ZQ,Ulfendahl M,Olivius NP.NGF stimulates extensive neurite outgrowthfromimplanted dorsal root ganglion neuronsfollowingtrans-plantationinto the adult rat inner ear[J].Neurobilogy of Disease,2005,18:184.
12 Bennett MR,Gibson WG,Lemon G.Neuron cell death,nerve growth factor and neurotrophic models:50year on[J].Aut Neurosci,2002,95:1.