谷氨酸-天冬氨酸转运体在豚鼠耳蜗的分布
Distribution of the Glutamate-Aspartate Transporter in the Cochlea of Guinea Pig
纪育斌;王锦玲;邱建华;刘顺利;陈福权
1:第四军医大学西京医院全军耳鼻咽喉专科中心
2:第四军医大学西京医院全军耳鼻咽喉专科中心
3:第四军医大学西京医院全军耳鼻咽喉专科中心
4:第四军医大学西京医院全军耳鼻咽喉专科中心
1 FadenAI,DemediukP ,PanterSS ,etal.TheroleofexcitatoryaminoacidsandNMDAreceptorsintraumaticbraininjury[J].Science,1989,244:798.
2 KanaiY ,HedigerMA .Primarystructureandfunctionalcharacteriza tionofahigh-affinityglutamatetransporter[J].Nature,1992,360:467.
3 GegelashviviG ,SchousboeA .Cellulardistributionandkinetieproper tiesofhigh-affinityglutamatetransporters[J].BrainResBull,1998,45:233.
4 RothsteinJD ,Dykes-HobergM ,PardoCA ,etal.Knockoutofglu tamatetransportersrevealsamajorroleforastroglialtransportinexcito toxicityandclearanceofglutamate[J].Neuron,1996,16:675.
5 MatsudaK .Increaseinglutamate-aspartatetransporter(GLAST)mRNAduringkanamycin-inducedcochlearinsultinrats[J].HearRes,1999,133:1.
6 KanaiY ,NussbergerS ,RomeroMF .Electrogenicpropertiesoftheepithelialandneuronalhighaffinityglutamatetransporter[J].JBiolChem,1995,270:16561.
7 TakahshiM ,BillupsB ,RossiD ,etal.Theroleofglutamatetrans portersinglutamatehomeostasisinthebrain[J].JExpBiol,1997,200:401.
8 JabauonD ,ScanzianiM ,GahwilerBH ,etal.Acutedecreaseinnetglutamateuptakeduringenergydeprivation[J].ProcNatlAcadSciUSA ,2000,97:5610.
9 PillisJW ,RenJ,O’ReganMH .Transporterreversalasamechanismofglutamatereleasefromtheischemicratcerebralcortex:studieswithDL -threo-beta-benzyloxyaspartate[J].BrainRes,2000,868:105.