经鼓室微导管持续泵入庆大霉素治疗难治性梅尼埃病

Continuous Intratympanic Infusion of Gentamicin via a Microcatheter for the Treatment of Intractable Meniere's Disease

侯秋来;尹绍文;王建军;董吕华;黄建萍

1:浙江省临海市耳鼻咽喉研究所

2:临海市第二人民医院

3:浙江省临海市耳鼻咽喉研究所

4:浙江省临海市耳鼻咽喉研究所

摘要
目的观察经鼓室内微导管持续泵入庆大霉素治疗单侧难治性梅尼埃病的疗效。方法对21例单侧难治性梅尼埃病患者经耳后进路鼓室内插入微导管,在2天内用微量泵以0.1mlh的速度注入庆大霉素0.048g,然后观察眩晕、听力及耳鸣的变化。结果21例平均随访23个月,眩晕完全控制18例,明显减轻3例,其中有2例复发再次治疗后眩晕消失;听力无明显改变有15例,听力平均下降5.1~7.6dB的有5例,听力平均下降10.4dB以上者1例;耳鸣消失者9例,明显减轻者6例,不变者6例。结论经鼓室微导管持续泵入庆大霉素治疗难治性梅尼埃病,可有效地控制眩晕,改善耳鸣;对听力的损害较轻微,可作为单侧难治性梅尼埃病的首选治疗方法。
关键词
庆大霉素;微量泵;难治性梅尼埃病
基金项目(Foundation):
作者
侯秋来;尹绍文;王建军;董吕华;黄建萍
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