自体脂肪、筋膜移植用于声带填充术的实验研究

Vocal Fold Augmentation by Transplantation of Autologous Fat and Fascia: An Experimental Study

李明栋;隋军;王文慧;何晓光;叶聪俊

1:昆明医学院第一附属医院耳鼻咽喉科

2:昆明医学院第一附属医院耳鼻咽喉科

3:昆明医学院第一附属医院耳鼻咽喉科

4:昆明医学院第一附属医院耳鼻咽喉科

摘要
目的 应用自体脂肪、筋膜行声带填充治疗单侧声带麻痹,探讨这两种填充材料的疗效及应用前景。方法实验动物为狗,分为2组,A组2只分别以自体脂肪、筋膜行声带填充矫治左侧带麻痹而致的声门闭合不全,于术后8个月取材行透射电镜及光镜观察;B组9只分别于左侧声带植入自体脂肪,右侧声带植入自体筋膜各0.4ml,分别手术后1、3、5个月取材行光镜观察。结果 自体脂肪能存活于声带组织中,但吸收较明显,功能观察显示,疗效维持不超过5个月;自体筋膜可成功存活于声带,疗效可维持8个月以上。结论 自体脂肪吸收明显,疗效不能持久,仅能作为短期的声带填充材料;自体筋膜性质较为稳定,疗效持久,具有良好的应用前景。
关键词
声带麻痹;脂肪;筋膜;移植;自体;声带填充术
基金项目(Foundation):
作者
李明栋;隋军;王文慧;何晓光;叶聪俊
参考文献

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