碱性成纤维细胞生长因子对前庭毛细胞的保护作用
Protective Effect of Basic Fibroblast Growth Factor on Vestibular Hair Cells Injuryed by Neomycin in Vitro
熊敏;姜泗长;杨伟炎;张素珍;翟所强
1:广州军区广州总医院耳鼻咽喉科!广州510010
2:解放军总医院耳鼻咽喉科研究所
3:解放军总医院耳鼻咽喉科研究所
4:解放军总医院耳鼻咽喉科研究所
1 LowW ,DazertS ,BaridA .BasicFibroblastGrowthFactor (FGF -2 )protectsratcochlearhaircellsinorganotypicalculturefromaminogly cosideinjury[J] .JCellularPhysiology,1996 ,16 7:443.
2 BlackFO ,PeszneckerSC .Vestibularototoxicity[J] .OtolaryngologyClinofNorthAm ,1993,2 6 :713.
3 SchlessingerJ ,UllrichA .Growthfactorsignalingbyreceptortyrosinekinases[J] .Neuron ,1992 ,9:383 .
4 UllrichA ,schlessingerJ.Signaltransductionbyreceptorswithtyrosinekinaseactivity[J] .Cell,1990 ,6 1:2 0 3.
5 AmayaE ,MusciTJ ,KirschnerMW .ExpressionofadominantnegativemutantoftheFGFreceptordisruptsmesodermformationinXenopusembryos[J] .Cell,1991,6 6 :2 5 7.
6 HoneggerAM ,SchmidtA ,UllrichA .Evidenceforepidermalgrowthfactor(EGF)inducedintermolecularautophosphorylationoftheEGFreceptorsinlivingcell[J] .MolCellBiol,1990 ,10 :40 35 .
7 MargolisB ,BellotF ,HoneggerAM .Tyrosinekinaseactivityisessen tialfortheassociationphospholipaseC -gammawiththeepidermalgrowthfactorreceptor[J] .MolCellBiol,1990 ,10 :435 .
8 MohammadiM ,DjonneC ,LiW .PointmutationinFGFreceptorelimi natesphospoinositidehydrolysiswithoutaffectingmitogenesis[J] .Na ture ,1992 ,35 8:6 81.
9 HaseM ,ArikiS ,KajiK .Classificationofsignalsforblockingapoptol sisinvascularendothelialcell[J] .JBiochem ,1995 ,116 :90 5 .
10YasudaT ,GrinspanJ,SternJ .Apoptosisoccursintheoligodendrogliallineage ,andispreventedbybasicFGF[J] .JNeurosciRes ,1995 ,40 :30 6 .