嗓音质量指数在汉语普通话人群中的效度和诊断价值

Validity and Diagnostic Accuracy of Acoustic Voice Quality Index in Mandarin Chinese Language

郭婷婷;李革临;侯倩;钟静婷;任慧;张驰

1:首都医科大学附属北京友谊医院耳鼻咽喉头颈外科

摘要
目的 探究嗓音质量指数(acoustic voice quality index, AVQI)在汉语普通话人群中的效度,能否区分正常与异常嗓音以及能否区分主观听觉感知的嗓音障碍严重程度。方法 纳入59例正常嗓音者及217例异常嗓音受试者,采集持续元音/a/和汉语连续言语样本,用Praat软件计算AVQI(v02.06),5名评分者进行GRBAS评分中的G评分,取其平均值Gmean,计算两者spearman相关系数,以Gmean=0.2作为异常嗓音的临界值,绘制ROC曲线,评估AVQI区分正常与异常嗓音以及不同严重程度嗓音障碍的诊断价值。结果 AVQI与Gmean的相关系数r=0.756(P<0.001)。区分正常与异常嗓音时,以Gmean=0.2作为临界值,AUC=0.849,临界值2.905;以临床诊断作为区分标准,AUC=0.788,临界值为3.18。区分嗓音障碍严重程度时,正常vs轻度异常AUC=0.770,临界值为1.985;轻度异常vs中度异常AUC=0.755,临界值为4.17;中度异常vs重度异常AUC=0.799,临界值为6.36。结论 AVQI是一种评估汉语普通话人群嗓音总体情况的快速、简便的工具,能够有效区分正常嗓音及异常嗓音,并能在一定程度上区分异常嗓音严重程度。

【Abstract] Objective To study the validity of acoustic voice quality index (AVQI) in Mandarin Chinese lan- guage, to investigate the accuracy of AVQI in discriminating normal and dysphonic voice, and the accuracy in discriminating across the perceptual categories of dysphonia severity. Methods This study included 59 subjects with normal voice and 217 subjects with dysphonic. Voice samples of sustained vowel /a/ and continuous speech were collected. AVQI was calculated using AVQI (v02. 06) script in Praat software. G score of GRBAS system was assessed by 5 raters and the mean value was used in following analysis. Spearman correlation coefficient was calculated. ROC curves were drawn to evaluate the accuracy of discriminating normal and dysphonic voice, and discriminating across the perceptual categories of dysphonia severity. Results The correlation coefficient of AVQI and Gmean was 0. 756 (P<0.001).When discriminating normal and dysphonic voice at Gmean=0.2,AUC=0.849 and threshold was 2. 905. When discriminating them under clinical diagnosis, AUC was 0. 788 and threshold was 3. 18. When discriminating voice of different severity, AUC and threshold of normal vs slight were 0.770 and 1.985 respectively. Those of slight vs moderate were 0. 755 and 4. 17, and those of moderate vs severe were 0. 799 and 6.36 respectively. Conclusion The AVQI is an easy-to-use and quick tool for the objective measure of overall voice quality in Mandarin Chinese language. It could discriminate normal and dysphonic voice, and the voice with different dysphonia severity to a certain extent.


关键词
嗓音质量指数;汉语普通话;嗓音障碍;多维度测量
基金项目(Foundation):
国家自然科学基金(81900926);; 北京自然科学基金(7204246)
作者
郭婷婷;李革临;侯倩;钟静婷;任慧;张驰
参考文献

1 Maryn Y,Roy N,De Bodt M,et al.Acoustic measurement of overall voice quality:a meta-analysis[J].The Journal of the Acoustical Society of America,2009,126(5):2619-2634.

2 Maryn Y,Corthals P,Van Cauwenberge P,et al.Toward improved ecological validity in the acoustic measurement of overall voice quality:combining continuous speech and sustained vowels[J].J Voice,2010,24(5):540-555.

3 Barsties VLB,Lehnert B,Janotte B.Validation of the acoustic voice quality index version 03.01 and acoustic breathiness index in German[J].J Voice,2020,34(1):157 e17-e25.

4 Pommee T,Maryn Y,Finck C,et al.Validation of the acoustic voice quality index,version 03.01,in French[J].J Voice,2020,34(4):646 e11-e26.

5 Kim GH,Lee YW,Bae IH,et al.Validation of the acoustic voice quality index in the Korean language[J].J Voice,2019,33(6):948 e1-e9.

6 李曙光,牛燕燕,祝小莉,等.嗓音质量指数在汉语普通话人群中的适用性初测[J].中国中西医结合耳鼻咽喉科杂志,2021,29(6):450-454,439.

7 Kishore Pebbili G,Shabnam S,Pushpavathi M,et al.Diagnostic accuracy of acoustic voice quality index version 02.03 in discriminating across the perceptual degrees of dysphonia severity in Kannada language[J].J Voice,2021,35(1):159 e11-e18.

8 Jayakumar T,Benoy JJ.Acoustic voice quality index (AVQI) in the measurement of voice quality:a systematic review and meta-analysis[J].J Voice,2022.S0892-1997(22)00084-4.

9 Awan SN,Solomon NP,Helou LB,et al.Spectral-cepstral estimation of dysphonia severity:external validation[J].Ann Otol Rhinol Laryngol,2013,122(1):40-48.

10 Sobol M,Sielska-Badurek EM.The dysphonia severity index (DSI)-normative values.Systematic review and meta-analysis[J].J Voice,2022,36(1):143.e9-e13.

11 Reynolds V,Buckland A,Bailey J,et al.Objective assessment of pediatric voice disorders with the acoustic voice quality index[J].J Voice,2012,26(5):672 e1-7.

12 Maryn Y,De Bodt M,Barsties B,et al.The value of the acoustic voice quality index as a measure of dysphonia severity in subjects speaking different languages[J].Eur Arch Otorhinolaryngol,2014,271(6):1609-1619.

13 Kankare E,Barsties VLB,Maryn Y,et al.The acoustic voice quality index version 02.02 in the Finnish-speaking population[J].Logopedics,Phoniatrics,Vocology,2020,45(2):49-56.

14 Yesilli-Puzella G,Tadihan-Ozkan E,Maryn Y.Validation and test-retest reliability of acoustic voice quality index version 02.06 in the Turkish language[J].J Voice,2020,S0892-1997(20)30322-2.

15 Barsties B,Maryn Y.The acoustic voice quality index.Toward expanded measurement of dysphonia severity in German subjects[J].HNO,2012,60(8):715-720.

16 Lee Y,Kim G,Kwon S.The usefulness of auditory perceptual assessment and acoustic analysis for classifying the voice severity[J].J Voice,2020,34(6):884-893.

17 Englert M,Lopes L,Vieira V,et al.Accuracy of acoustic voice quality index and its isolated acoustic measures to discriminate the severity of voice disorders[J].J Voice,2020,36(4):582.e1-582.e10.

18 Barsties VLB,Ulozaite-Staniene N,Petrauskas T,et al.Diagnostic accuracy of dysphonia classification of DSI and AVQI[J].Laryngoscope,2019,129(3):692-698.