miRNA在老年性听力损失发病机制中的研究进展

张梦娴;王青玲;郭向东

1:河南中医药大学

2:河南中医药大学第一附属医院

摘要
<正>老年性听力损失(age-related hearing loss, AHL)是指随年龄的增长,双耳出现渐进性、对称性的感音神经性听力损失。发达国家老年性听力损失的发病率约为25%~40%,AHL不仅影响人际交流、降低生活质量,还会导致焦虑、抑郁和认知障碍,给家庭和社会造成重大负担~([1])。AHL的发病机制复杂,可能与耳蜗神经细胞的凋亡、自噬、氧化应激和炎症反应等密切相关~([2])。微小核糖核酸(micro ribonucleic acid,
关键词
基金项目(Foundation):
河南省科技攻关计划(192102310170,202102310174);; 河南省中医药科学研究专项重点课题(20-21ZY1045)
作者
张梦娴;王青玲;郭向东
参考文献

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张梦娴王青玲郭向东